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Medicines (732)

Medicines > classes

: Classic Psychedelic

or Dissociative

or Sedative-hypnotic

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Other values:

None (95) · (none, never marketed) (1) · Dalmane (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Doral (1) · Doriden (1) · DXM (1) · DXO (1) · Halcion (1) · Hetlioz (1) · Imovane (1) · Lunesta (1) · Mogadon (1) · Nembutal (1) · Placidyl (1) · ProSom (1) · Quaalude (1) · Restoril (1) · Rohypnol (1) · Rozerem (1) · Seconal (1) · Sonata (1) · Spravato (1) · THIP (1) · Versed (1) · Xyrem (1)

5-HT2A agonist (26) · GABAA positive allosteric modulator (15) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · None (3) · GABAA positive allosteric modulator (non-benzodiazepine) (3) · NMDA antagonist (3) · Contains LSA (2) · Contains mescaline (2) · GABAA potentiator and direct activator (2) · Melatonin receptor agonist (2) · NMDA antagonist; sigma receptor agonist (2)

Other values:

None (118) · No approved medical problem. Encountered as a designer/research benzodiazepine and, increasingly, as an adulterant in illicit opioid supplies. (1) · Treatment-resistant depression (TRD) in adults, as adjunct to oral antidepressant (FDA-approved March 2019). Depressive symptoms in adults with MDD with acute suicidal ideation or behavior (FDA-approved Aug 2020). (1)

None (118) · Induction (TRD): 56 mg intranasal twice weekly × 4 weeks. Maintenance: 56-84 mg once weekly × 4 weeks, then 56-84 mg every 1-2 weeks. For acute suicidality: 84 mg twice weekly × 4 weeks. Administered under medical supervision in REMS-certified site. (1) · No medical dose. Active recreational doses reported in the 0.5–1.5 mg range (similar potency to alprazolam). (1)

None (118) · 28 mg/device (each dose uses 2 devices) (1) · Illicit tablets ("bars"), powders, blotter, occasionally solutions. No pharmaceutical product exists. (1)

None (118) · 84 mg per session (1) · N/A (never approved) (1)

None (117) · Intranasal (under direct medical supervision) (1) · intranasal; rectal and IV reported. (1) · Oral (2) · sublingual (1)

None (117) · 30–60 minutes (1) · Within hours of first administration (1) · ~20–40 min PO; faster sublingual/intranasal. (1)

None (117) · 6–10 h subjective; full pharmacologic effect considerably longer. (1) · 8–12 hours (1) · Acute effect ~24 hours; cumulative effect builds with repeated dosing (1)

None (117) · 3–5 hours (1) · Estimated ~12–17 h (some sources cite up to ~21 h); active metabolites prolong effect. (1) · ~7-12 hours (1)

None (117) · 70–90% (oral) (1) · Not formally characterized in humans. (1) · ~48% intranasal (1)

None (117) · Avoid. Benzodiazepines are associated with neonatal sedation, floppy-infant syndrome, and withdrawal; teratogenic signal weak but non-zero. Designer benzo with no safety data, assume worst-case. (1) · Avoid; may cause fetal harm (1) · Not established (1)

None (118) · Rx, Schedule III (US). REMS program required. (1) · Schedule I (United States) (1)

Showing below up to 120 results in range #1 to #120.

1

2

3

4

5

A

B

C

Clonazolam

D

E

F

G

H

Hawaiian Baby Woodrose

I

Ibogaine

L

M

N

O

O-PCE

P

Q

Quazepam

R

Ramelteon

S

T

X

Xenon

Y

Yopo

Z

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