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Drilldown: Medicines

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Medicines > classes : Classic Psychedelic or Neuroleptic or Serotonin partial agonist reuptake inhibitor (SPARI)

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generic:
brand:
None (69) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Fanapt (1) · Geodon (1) · Inapsine (1) · Invega (1) · Latuda (1) · Loxitane (1) · Mellaril (1) · Moban (1) · Navane (1) · Orap (1) · Prolixin (1) · Saphris (1) · Stelazine (1) · Thorazine (1) · Trilafon (1) · Viibryd (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Phenothiazine D2 antagonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (85) · Major depressive disorder in adults (FDA-approved 2011) (1)
starting dose:
None (85) · 10 mg PO once daily × 7 days, then 20 mg × 7 days, then 40 mg as target dose (take with food) (1)
preparations:
None (85) · 10 mg, 20 mg, 40 mg tablets (1)
fda max:
None (85) · 40 mg/d (1)
routes:
None (84) · Oral (2)
onset:
None (84) · 30–60 minutes (1) · 4-6 weeks for full antidepressant effect (claimed earlier onset for some patients due to 5HT1A partial agonism) (1)
duration:
None (84) · 8–12 hours (1) · Daily dosing (1)
halflife:
None (84) · 3–5 hours (1) · ~25 hours (1)
bioavailability:
None (84) · 70–90% (oral) (1) · ~72% (with food); much lower fasting (~36%) (1)
pregnancy:
None (84) · Limited data; weigh benefits/risks (1) · Not established (1)
legal:
None (84) · Rx (1) · Schedule I (United States) (1)

Showing below up to 86 results in range #1 to #86.

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