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Medicines > classes : Empathogen or [[:Category:Incretin_modulators|Incretin pathway modulator]] & fda max: 5 mg/d

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generic:
Linagliptin (1)
brand:
Tradjenta; with metformin Jentadueto (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000117B-QINU`"' (1)
starting dose:
5 mg PO once daily (no renal dose adjustment, unlike sitagliptin) (1)
preparations:
5 mg tablets; combination with metformin (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
Postprandial glucose effect within days; HbA1c by 12 weeks (1)
duration:
24 hours (1)
halflife:
~12 hours (effective); terminal much longer'"`UNIQ--ref-0000117C-QINU`"' (1)
bioavailability:
~30% (oral)'"`UNIQ--ref-0000117D-QINU`"' (1)
pregnancy:
Limited data; switch to insulin where feasible.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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