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Medicines > classes : Neuroleptic or [[:Category:Sulfonylureas|Sulfonylurea (second-generation)]]

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generic:
Asenapine (1) · Chlorpromazine (1) · Clozapine (1) · Droperidol (1) · Fluphenazine (1) · Glipizide (1) · Iloperidone (1) · Loxapine (1) · Lurasidone (1) · Molindone (1) · Paliperidone (1) · Perphenazine (1) · Pimozide (1) · Thioridazine (1) · Thiothixene (1) · Trifluoperazine (1) · Ziprasidone (1)
brand:
Clozaril (1) · Fanapt (1) · Geodon (1) · Glucotrol, Glucotrol XL (1) · Inapsine (1) · Invega (1) · Latuda (1) · Loxitane (1) · Mellaril (1) · Moban (1) · Navane (1) · Orap (1) · Prolixin (1) · Saphris (1) · Stelazine (1) · Thorazine (1) · Trilafon (1)
classes: (Click arrow to add another value)
mechanism:
Butyrophenone D2 antagonist (1) · D2 receptor antagonist; also H1, alpha-1, muscarinic antagonist (1) · D2/5-HT2A antagonist (1) · D2/5-HT2A antagonist; 5-HT7 antagonist (1) · D2/5-HT2A antagonist; active metabolite of risperidone (1) · D2/5-HT2A antagonist; SRI and NRI (1) · Dibenzoxazepine D2/5-HT2 antagonist (1) · Dihydroindolone D2 antagonist (1) · Diphenylbutylpiperidine D2 antagonist (1) · Multi-receptor antagonist (D2, 5-HT2A, H1, alpha) (1) · Multi-receptor antagonist; low D2 affinity (1) · Phenothiazine D2 antagonist (4) · Thioxanthene D2 antagonist (1) · '"`UNIQ--vote-000002D7-QINU`"' Hypoglycemia is the central risk, especially in elderly and renally impaired patients (glipizide has shorter half-life than glyburide, which is one reason it is preferred in older adults). CYP2C9 substrate; weight gain typical. (1)
uses:
None (16) · '"`UNIQ--vote-000002D8-QINU`"' (1)
starting dose:
None (16) · 5 mg PO once daily, 30 minutes before breakfast; XL: 5 mg with breakfast (1)
preparations:
None (16) · 5 mg, 10 mg immediate-release tablets; 2.5 mg, 5 mg, 10 mg extended-release tablets (1)
fda max:
None (16) · 40 mg/d (IR; doses >15 mg given as divided BID); 20 mg/d (XL) (1)
routes:
None (16) · Oral (1)
onset:
None (16) · Within 30 minutes (IR) (1)
duration:
None (16) · ~12-24 hours (1)
halflife:
None (16) · 2-5 hours'"`UNIQ--ref-000002D9-QINU`"' (1)
bioavailability:
None (16) · ~100% (oral; food delays absorption, hence pre-meal dosing for IR)'"`UNIQ--ref-000002DA-QINU`"' (1)
pregnancy:
None (16) · Avoid; switch to insulin. Hypoglycemia in newborn reported.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (16) · [[USLegal:Prescription only|Rx-only]] in US (1)

Showing below up to 17 results in range #1 to #17.

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