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Drilldown: Medicines

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Medicines > classes : Phenethylamine or [[:Category:Sigma-1_receptor_agonists|Sigma-1 receptor agonist]]

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generic:
25B-NBOH (1) · 25B-NBOMe (1) · 25C-NBOH (1) · 25C-NBOMe (1) · 25I-NBOH (1) · 25I-NBOMe (1) · 25N-NBOMe (1) · 2C-B (1) · 2C-B-FLY (1) · 2C-C (1) · 2C-D (1) · 2C-E (1) · 2C-I (1) · 2C-P (1) · 2C-T-2 (1) · 2C-T-7 (1) · Allylescaline (1) · Bromo-DragonFLY (1) · DOB (1) · DOC (1) · DOI (1) · DOM (1) · Escaline (1) · Methallylescaline (1) · Phencyclidine (1) · Proscaline (1) · TMA-2 (1)
brand:
None (25) · Nexus, Eroxan (historical, late-1980s through mid-1990s) (1) · Sernyl (human, withdrawn 1965); Sernylan (veterinary, withdrawn 1978) (1)
classes: (Click arrow to add another value)
mechanism:
None (1) · 5-HT2A agonist (12) · 5-HT2A agonist; long duration (1) · 5-HT2A agonist; MAO inhibitor (1) · 5-HT2A agonist; milder than other 2C-x (1) · 5-HT2A partial agonist (1) · Extremely potent 5-HT2A agonist; vasoconstrictor (1) · Extremely potent 5-HT2A agonist; very long duration (1) · Potent 5-HT2A agonist (5) · Potent 5-HT2A agonist; no oral activity (1) · Potent 5-HT2A agonist; very long duration (1) · Very potent 5-HT2A agonist; long duration (1)
uses:
None (26) · '"`UNIQ--vote-00000063-QINU`"', '"`UNIQ--vote-00000064-QINU`"' (1)
starting dose:
None (26) · No current medical indication. Historical anesthetic dose 0.25 mg/kg IV (Sernyl). (1)
preparations:
None (26) · Historical: Sernyl 25 mg tablets, 10 mg/mL injection (human); Sernylan 100 mg/mL injection (veterinary). Illicit: white crystalline powder, oily liquid, "dipped" cigarettes ("wet"), tablets. (1)
fda max:
None (26) · N/A (no current medical indication) (1)
routes:
None (25) · IM (1) · insufflated (2) · IV (1) · Oral (2) · PR (1) · smoked (1)
onset:
None (25) · 45-75 min (oral) (1) · Smoked 2-5 min; insufflated 5-15 min; oral 30-60 min; IV / IM ~5-15 min (1)
duration:
None (25) · 4-8 h (1) · 4-8 hours typical; longer at high doses; residual cognitive and perceptual effects up to 48 hours (1)
halflife:
None (25) · Highly variable, 7-46 hours (mean ~21 h); lipophilic deposition in fat with delayed re-release contributes to wide range'"`UNIQ--ref-00000065-QINU`"' (1) · Not well characterized (1)
bioavailability:
None (25) · Not well characterized (1) · ~72% oral; ~85% smoked'"`UNIQ--ref-00000066-QINU`"' (1)
pregnancy:
None (26) · Not established (1)
legal:
None (25) · [[USLegal:DEA Schedule II|Schedule II]] controlled substance in US (rescheduled from Schedule III in 1978). No accepted medical use. UN Convention on Psychotropic Substances Schedule II internationally.'"`UNIQ--ref-00000067-QINU`"' (1) · [[USLegal:DEA Schedule I|Schedule I]] (United States) (1)

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