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Medicines > classes : Phenethylamine or Stimulant or [[:Category:Anesthetics|Anesthetic (historical)]]

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generic:
brand:
None (67) · Benzedrex (1) · Nexus, Eroxan (historical, late-1980s through mid-1990s) (1) · Sernyl (human, withdrawn 1965); Sernylan (veterinary, withdrawn 1978) (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (12) · Monoamine releasing agent (8) · Dopamine/norepinephrine reuptake inhibitor (5) · Potent 5-HT2A agonist (5) · Cathinone analogue; monoamine reuptake inhibitor (2) · Dopamine and norepinephrine reuptake inhibitor (2) · Norepinephrine–dopamine reuptake inhibitor (2)
uses:
None (69) · '"`UNIQ--vote-00000063-QINU`"', '"`UNIQ--vote-00000064-QINU`"' (1)
starting dose:
None (69) · No current medical indication. Historical anesthetic dose 0.25 mg/kg IV (Sernyl). (1)
preparations:
None (69) · Historical: Sernyl 25 mg tablets, 10 mg/mL injection (human); Sernylan 100 mg/mL injection (veterinary). Illicit: white crystalline powder, oily liquid, "dipped" cigarettes ("wet"), tablets. (1)
fda max:
None (69) · N/A (no current medical indication) (1)
routes:
None (68) · IM (1) · insufflated (2) · IV (1) · Oral (2) · PR (1) · smoked (1)
onset:
None (68) · 45-75 min (oral) (1) · Smoked 2-5 min; insufflated 5-15 min; oral 30-60 min; IV / IM ~5-15 min (1)
duration:
None (68) · 4-8 h (1) · 4-8 hours typical; longer at high doses; residual cognitive and perceptual effects up to 48 hours (1)
halflife:
None (68) · Highly variable, 7-46 hours (mean ~21 h); lipophilic deposition in fat with delayed re-release contributes to wide range'"`UNIQ--ref-00000065-QINU`"' (1) · Not well characterized (1)
bioavailability:
None (68) · Not well characterized (1) · ~72% oral; ~85% smoked'"`UNIQ--ref-00000066-QINU`"' (1)
pregnancy:
None (69) · Not established (1)
legal:
None (68) · [[USLegal:DEA Schedule II|Schedule II]] controlled substance in US (rescheduled from Schedule III in 1978). No accepted medical use. UN Convention on Psychotropic Substances Schedule II internationally.'"`UNIQ--ref-00000067-QINU`"' (1) · [[USLegal:DEA Schedule I|Schedule I]] (United States) (1)

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