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Drilldown: Medicines

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Medicines > classes : Research material or [[:Category:Sex_hormones|Sex hormone]] & pregnancy: None

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generic:
brand:
None (130) · O-DSMT (1) · Prometrium (oral), Endometrin (vaginal), Crinone (vaginal gel), Prochieve (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Monoamine releasing agent (9) · GABAA positive allosteric modulator (8) · CB1/CB2 agonist (7) · Dopamine/norepinephrine reuptake inhibitor (5) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Serotonin/norepinephrine/dopamine releasing agent (3) · Cathinone analogue; monoamine reuptake inhibitor (2) · Dopamine and norepinephrine reuptake inhibitor (2) · NMDA antagonist (2) · Prodrug of GHB (2)
uses:
None (131) · '"`UNIQ--vote-00000722-QINU`"', '"`UNIQ--vote-00000723-QINU`"', '"`UNIQ--vote-00000724-QINU`"', '"`UNIQ--vote-00000725-QINU`"' (1)
starting dose:
None (131) · HRT cyclic: 200 mg PO HS days 1-12 of each month; continuous: 100 mg PO daily; ART luteal support 100 mg vaginal TID or 90 mg gel daily (1)
preparations:
None (131) · Oral 100, 200 mg capsules (peanut oil; check allergy); 100 mg vaginal insert (Endometrin); 4%, 8% vaginal gel (Crinone); IM 50 mg/mL (1)
fda max:
None (131) · Indication-dependent; 200-400 mg/d oral typical (1)
routes:
None (131) · intramuscular (1) · Oral (1) · vaginal (1)
onset:
None (131) · Sedation/dizziness within hours of oral dose; endometrial effects over days (1)
duration:
None (131) · Oral: 8-12 hours; vaginal: 24+ hours; IM: days (1)
halflife:
None (131) · ~5-20 hours (oral micronized; highly variable)'"`UNIQ--ref-00000726-QINU`"' (1)
bioavailability:
None (131) · Oral: very low (extensive first-pass); micronization improves uptake somewhat. Vaginal: high local effect with lower systemic levels (first-uterine-pass concentration)'"`UNIQ--ref-00000727-QINU`"' (1)
pregnancy: (Click arrow to add another value)
legal:
None (131) · [[USLegal:Prescription only|Rx-only]] in US (1)

Showing below up to 132 results in range #1 to #132.

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