Drilldown: Medicines
Medicines > classes 
:
Sedative-Hypnotic or
Stimulant or
[[:Category:Antimigraine medicines|Antimigraine medicine]]
:
Sedative-Hypnotic or
Stimulant or
[[:Category:Antimigraine medicines|Antimigraine medicine]] Use the filters below to narrow your results.
generic:
brand:
None (51) ·
(none, never marketed) (1) ·
Benzedrex (1) ·
Dalmane (1) ·
Doral (1) ·
Doriden (1) ·
Halcion (1) ·
Hetlioz (1) ·
Imitrex (oral, injectable, nasal), Tosymra (nasal spray), Onzetra Xsail (nasal powder), Zembrace SymTouch (low-dose autoinjector), Sumavel DosePro (needle-free SC) (1) ·
Imovane (1) ·
Lunesta (1) ·
Maxalt (tablet), Maxalt-MLT (orally disintegrating tablet) (1) ·
Mogadon (1) ·
Nembutal (1) ·
Nurtec ODT (1) ·
Placidyl (1) ·
ProSom (1) ·
Quaalude (1) ·
Restoril (1) ·
Rohypnol (1) ·
Rozerem (1) ·
Seconal (1) ·
Sonata (1) ·
THIP (1) ·
Versed (1) ·
Xyrem (1)
classes: (Click arrow to add another value)
mechanism:
GABAA positive allosteric modulator (15) ·
Monoamine releasing agent (8) ·
None (5) ·
Dopamine/norepinephrine reuptake inhibitor (5) ·
GABAA positive allosteric modulator (non-benzodiazepine) (3) ·
Cathinone analogue; monoamine reuptake inhibitor (2) ·
Dopamine and norepinephrine reuptake inhibitor (2) ·
GABAA potentiator and direct activator (2) ·
Melatonin receptor agonist (2) ·
Norepinephrine–dopamine reuptake inhibitor (2)
uses:
starting dose:
None (72) ·
5-10 mg PO at migraine onset; may repeat after 2 hours, maximum 30 mg/24 hours (1) ·
Acute migraine: 75 mg PO at onset, maximum one dose per 24 hours. Preventive: 75 mg PO every other day (1) ·
No medical dose. Active recreational doses reported in the 0.5–1.5 mg range (similar potency to alprazolam). (1) ·
Oral: 50-100 mg at migraine onset, may repeat in 2 hours if needed. SC: 6 mg, may repeat in 1 hour. Nasal: 5-20 mg per nostril, may repeat in 2 hours (1)
preparations:
None (72) ·
Illicit tablets ("bars"), powders, blotter, occasionally solutions. No pharmaceutical product exists. (1) ·
Oral tablets 25, 50, 100 mg; SC injection 4, 6 mg autoinjector; needle-free SC 6 mg (Sumavel); nasal spray 5, 20 mg; nasal powder 22 mg (Onzetra Xsail); low-dose autoinjector 3 mg (Zembrace SymTouch) (1) ·
Orally disintegrating tablet 75 mg (1) ·
Tablets 5, 10 mg; ODT (Maxalt-MLT) 5, 10 mg (1)
fda max:
routes:
onset:
duration:
halflife:
bioavailability:
None (72) ·
Not formally characterized in humans. (1) ·
~14% (oral; substantial first-pass); ~97% (subcutaneous); ~17% (nasal)'"`UNIQ--ref-00000016-QINU`"' (1) ·
~45% (oral; substantially higher than sumatriptan's ~14%)'"`UNIQ--ref-00000013-QINU`"' (1) ·
~64% (oral)'"`UNIQ--ref-00000016-QINU`"' (1)
pregnancy:
None (72) ·
Avoid. Benzodiazepines are associated with neonatal sedation, floppy-infant syndrome, and withdrawal; teratogenic signal weak but non-zero. Designer benzo with no safety data, assume worst-case. (1) ·
Limited human data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) ·
Limited human data; pregnancy registry data have been broadly reassuring across the triptan class.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) ·
Limited human data; pregnancy registry data have been broadly reassuring relative to baseline malformation rates.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)
Showing below up to 76 results in range #1 to #76.