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Medicines > classes : Serotonin partial agonist reuptake inhibitor (SPARI) or Stimulant or Tryptamine

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generic:
brand:
None (67) · Benzedrex (1) · Viibryd (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (15) · Monoamine releasing agent (8) · Dopamine/norepinephrine reuptake inhibitor (5) · Cathinone analogue; monoamine reuptake inhibitor (2) · Dopamine and norepinephrine reuptake inhibitor (2) · Norepinephrine–dopamine reuptake inhibitor (2)
uses:
None (68) · Major depressive disorder in adults (FDA-approved 2011) (1)
starting dose:
None (68) · 10 mg PO once daily × 7 days, then 20 mg × 7 days, then 40 mg as target dose (take with food) (1)
preparations:
None (68) · 10 mg, 20 mg, 40 mg tablets (1)
fda max:
None (68) · 40 mg/d (1)
routes:
None (68) · Oral (1)
onset:
None (68) · 4-6 weeks for full antidepressant effect (claimed earlier onset for some patients due to 5HT1A partial agonism) (1)
duration:
None (68) · Daily dosing (1)
halflife:
None (68) · ~25 hours (1)
bioavailability:
None (68) · ~72% (with food); much lower fasting (~36%) (1)
pregnancy:
None (68) · Limited data; weigh benefits/risks (1)
legal:
None (68) · Rx (1)

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