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Drilldown: Medicines

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Medicines > classes : Stimulant or [[:Category:Antihypertensives|Antihypertensive]] & fda max: 50 mg/d (hypertension); up to 200 mg/d (edema)

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generic:
Hydrochlorothiazide (1)
brand:
Microzide; mostly prescribed generically (1)
classes: (Click arrow to add another value)
mechanism:
'"`UNIQ--vote-00000138-QINU`"' Decreases urinary calcium (used in stone prevention); raises serum uric acid, glucose, and lipids modestly; non-anion-gap hypokalemic metabolic alkalosis is the characteristic electrolyte pattern'"`UNIQ--ref-00000139-QINU`"'. (1)
uses:
'"`UNIQ--vote-0000013A-QINU`"', '"`UNIQ--vote-0000013B-QINU`"', '"`UNIQ--vote-0000013C-QINU`"', '"`UNIQ--vote-0000013D-QINU`"' (1)
starting dose:
12.5-25 mg PO once daily (1)
preparations:
12.5 mg capsules; 12.5, 25, 50 mg tablets (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
Diuresis at 2 hours; antihypertensive effect within days, max at 3-4 weeks (1)
duration:
6-12 hours (1)
halflife:
6-15 hours'"`UNIQ--ref-0000013E-QINU`"' (1)
bioavailability:
65-75% (oral)'"`UNIQ--ref-0000013F-QINU`"' (1)
pregnancy:
None (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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