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Drilldown: Medicines

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Medicines > classes : Stimulant or Tryptamine or [[:Category:Androgen_modulators|Androgen modulator]]

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generic:
brand:
None (67) · Avodart; combined with tamsulosin as Jalyn (1) · Benzedrex (1) · Proscar (5 mg, BPH), Propecia (1 mg, alopecia) (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (15) · Monoamine releasing agent (8) · Dopamine/norepinephrine reuptake inhibitor (5) · None (2) · Cathinone analogue; monoamine reuptake inhibitor (2) · Dopamine and norepinephrine reuptake inhibitor (2) · Norepinephrine–dopamine reuptake inhibitor (2)
uses:
None (68) · '"`UNIQ--vote-0000052E-QINU`"', '"`UNIQ--vote-0000052F-QINU`"', '"`UNIQ--vote-00000530-QINU`"' (1) · '"`UNIQ--vote-00000D57-QINU`"', '"`UNIQ--vote-00000D58-QINU`"' (1)
starting dose:
None (68) · 0.5 mg PO once daily (1) · 5 mg PO daily for BPH; 1 mg PO daily for androgenetic alopecia (1)
preparations:
None (68) · 0.5 mg capsules (1) · 1 mg, 5 mg tablets (1)
fda max:
None (68) · 0.5 mg/d (1) · 5 mg/d (1)
routes:
None (68) · Oral (2)
onset:
None (68) · BPH symptom improvement at 3-6 months; prostate volume reduction over 6-12 months; hair regrowth at 6-12 months (1) · Prostate volume reduction over 6-12 months (1)
duration:
None (68) · 24 hours (1) · 24 hours; tissue effects persist weeks (1)
halflife:
None (68) · ~5 weeks (much longer than finasteride's ~6 hours)'"`UNIQ--ref-00000D59-QINU`"' (1) · ~5-6 hours in young men, ~8 hours in elderly'"`UNIQ--ref-00000531-QINU`"' (1)
bioavailability:
None (68) · ~60% (oral)'"`UNIQ--ref-00000D5A-QINU`"' (1) · ~63% (oral)'"`UNIQ--ref-00000532-QINU`"' (1)
pregnancy:
None (68) · '''Pregnant individuals should not handle crushed/broken tablets''' (skin absorption risk); can cause hypospadias in male fetus. Not used in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1) · '''Pregnant individuals should not handle dutasteride capsules''' (skin absorption risk through intact capsule); can cause hypospadias in male fetus.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
None (68) · [[USLegal:Prescription only|Rx-only]] in US (2)

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