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Drilldown: Medicines

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Medicines > classes : Stimulant or Tryptamine or [[:Category:Incretin_modulators|Incretin pathway modulator]]

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generic:
brand:
None (67) · Benzedrex (1) · Januvia; with metformin Janumet/Janumet XR (1) · Tradjenta; with metformin Jentadueto (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (15) · Monoamine releasing agent (8) · Dopamine/norepinephrine reuptake inhibitor (5) · Cathinone analogue; monoamine reuptake inhibitor (2) · Dopamine and norepinephrine reuptake inhibitor (2) · Norepinephrine–dopamine reuptake inhibitor (2)
uses:
None (68) · '"`UNIQ--vote-00000764-QINU`"' (1) · '"`UNIQ--vote-0000117B-QINU`"' (1)
starting dose:
None (68) · 100 mg PO once daily (50 mg if CrCl 30-44; 25 mg if <30 or dialysis) (1) · 5 mg PO once daily (no renal dose adjustment, unlike sitagliptin) (1)
preparations:
None (68) · 25, 50, 100 mg tablets; combination tablets with metformin (1) · 5 mg tablets; combination with metformin (1)
fda max:
None (68) · 100 mg/d (1) · 5 mg/d (1)
routes:
None (68) · Oral (2)
onset:
None (68) · Postprandial glucose effect within days; HbA1c by 12 weeks (2)
duration:
None (68) · 24 hours (2)
halflife:
None (68) · ~12 hours (effective); terminal much longer'"`UNIQ--ref-0000117C-QINU`"' (1) · ~12.4 hours'"`UNIQ--ref-00000765-QINU`"' (1)
bioavailability:
None (68) · ~30% (oral)'"`UNIQ--ref-0000117D-QINU`"' (1) · ~87% (oral)'"`UNIQ--ref-00000766-QINU`"' (1)
pregnancy:
None (68) · Limited data; switch to insulin where feasible.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (2)
legal:
None (68) · [[USLegal:Prescription only|Rx-only]] in US (2)

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