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Medicines (732)

Medicines > classes: [[:Category:Antianginals|Antianginal]]

& routes

: IV/IM (Buprenex). Oral swallowed: very low bioavailability due to first-pass; not therapeutic.

or Oral

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Amlodipine (1) · Isosorbide (dinitrate, mononitrate) (1)

Imdur (mononitrate ER), Isordil (dinitrate); generics; with hydralazine as BiDil for HFrEF in self-identified Black patients (1) · Norvasc, Katerzia (1)

None (1) · '"`UNIQ--vote-00000073-QINU`"' The long half-life gives smooth, once-daily BP control with low rebound. CYP3A4 substrate; pedal edema is the characteristic, dose-related, non-fluid-overload side effect'"`UNIQ--ref-00000074-QINU`"'. (1)

'"`UNIQ--vote-00000075-QINU`"', '"`UNIQ--vote-00000076-QINU`"', '"`UNIQ--vote-00000077-QINU`"' (1) · '"`UNIQ--vote-0000145E-QINU`"', '"`UNIQ--vote-0000145F-QINU`"', '"`UNIQ--vote-00001460-QINU`"' (1)

2.5-5 mg PO once daily; titrate to 10 mg/d (1) · Isosorbide mononitrate ER: 30-60 mg PO once daily in the morning, titrate to 120-240 mg/d; isosorbide dinitrate IR: 5-20 mg PO TID with a 12-14 hour nitrate-free interval to prevent tolerance (1)

2.5, 5, 10 mg tablets; 1 mg/mL oral suspension (1) · Mononitrate 10, 20 mg IR; 30, 60, 120 mg ER; dinitrate 5, 10, 20, 30, 40 mg IR and ER (1)

10 mg/d (1) · 240 mg/d (mononitrate ER); 160 mg/d (dinitrate) (1)

BP effect within 24 hours; full effect at 1-2 weeks (long half-life) (1) · SL: 2-5 minutes; PO mononitrate: 30-60 minutes (1)

24 hours (1) · Mononitrate ER: 12-24 hours; dinitrate IR: 4-6 hours (1)

30-50 hours'"`UNIQ--ref-00000078-QINU`"' (1) · Mononitrate ~5 hours; dinitrate ~1 hour'"`UNIQ--ref-00001461-QINU`"' (1)

64-90% (oral; not affected by food)'"`UNIQ--ref-00000079-QINU`"' (1) · Mononitrate ~100% (no first-pass; the principal advantage over dinitrate); dinitrate ~20%'"`UNIQ--ref-00001462-QINU`"' (1)

Limited data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) · Limited data; case series and registries suggest no major teratogenicity but other antihypertensives (labetalol, nifedipine) are typically preferred.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

[[USLegal:Prescription only|Rx-only]] in US (2)

Showing below up to 2 results in range #1 to #2.

A

Amlodipine

I

Isosorbide

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