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Medicines > classes: [[:Category:Antihistamines|Antihistamine]] & fda max: 5 mg/d (adults) & duration: 24 hours

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generic:
Levocetirizine (1)
brand:
Xyzal, Xyzal Allergy 24HR (OTC) (1)
classes: (Click arrow to add another value)
mechanism:
'"`UNIQ--vote-00000950-QINU`"' Mostly renally cleared unchanged; dose-reduce in renal impairment. Like cetirizine, retains slightly more sedation than fexofenadine in some users'"`UNIQ--ref-00000951-QINU`"'. (1)
uses:
'"`UNIQ--vote-00000952-QINU`"', '"`UNIQ--vote-00000953-QINU`"' (1)
starting dose:
5 mg PO once daily in the evening (1)
preparations:
5 mg tablets; 2.5 mg/5 mL oral solution; OTC (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
30-60 minutes (1)
duration: (Click arrow to add another value)
halflife:
~8 hours (longer in elderly and renal impairment)'"`UNIQ--ref-00000954-QINU`"' (1)
bioavailability:
~85-90% (oral; not significantly affected by food)'"`UNIQ--ref-00000955-QINU`"' (1)
pregnancy:
Generally considered safe; widely used. Cetirizine and loratadine remain the more-studied alternatives.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
OTC in US (1)

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