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Medicines > classes: [[:Category:Antihistamines|First-generation antihistamine]] & duration : 24 h or 6-8 hours

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generic:
Cyproheptadine (hydrochloride) (1)
brand:
Periactin (US brand discontinued; generic widely available) (1)
classes: (Click arrow to add another value)
mechanism:
'"`UNIQ--vote-00000017-QINU`"' Anticholinergic and sedating, with the standard first-generation antihistamine Beers-list concerns in elderly patients'"`UNIQ--ref-00000018-QINU`"'. (1)
uses:
'"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"', '"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"' (1)
starting dose:
Allergy: 4 mg PO TID. Serotonin syndrome: 12 mg loading dose PO or by nasogastric tube, then 2 mg every 2 hours until clinical improvement. Appetite stimulation: 2-4 mg PO TID-QID (1)
preparations:
Tablets 4 mg; oral syrup 2 mg/5 mL (1)
fda max:
32 mg/day adult; weight-based pediatric ceiling (1)
routes:
Oral (1)
onset:
30-60 minutes (1)
duration: (Click arrow to add another value)
halflife:
8-16 hours'"`UNIQ--ref-0000001E-QINU`"' (1)
bioavailability:
~95% (oral)'"`UNIQ--ref-0000001F-QINU`"' (1)
pregnancy:
Limited human data; older agent with substantial use experience.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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