Drilldown: Medicines - Pharmacopedia

Nav

Choose a table:

Medicines (732)

Medicines > classes: [[:Category:Antihypertensives|Antihypertensive]]

& fda max

: 10 mg/d

or 50 mg BID in heart failure (or once-daily equivalent CR); 25 mg BID in hypertension

Use the filters below to narrow your results.

Amlodipine (1) · Carvedilol (1)

Coreg, Coreg CR (1) · Norvasc, Katerzia (1)

'"`UNIQ--vote-00000015-QINU`"' CYP2D6 metabolism produces stereoselective clearance; CYP2D6 poor metabolizers have higher plasma exposure and may need lower doses'"`UNIQ--ref-00000016-QINU`"'. (1) · '"`UNIQ--vote-00000073-QINU`"' The long half-life gives smooth, once-daily BP control with low rebound. CYP3A4 substrate; pedal edema is the characteristic, dose-related, non-fluid-overload side effect'"`UNIQ--ref-00000074-QINU`"'. (1)

'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"', '"`UNIQ--vote-0000001A-QINU`"' (1) · '"`UNIQ--vote-00000075-QINU`"', '"`UNIQ--vote-00000076-QINU`"', '"`UNIQ--vote-00000077-QINU`"' (1)

2.5-5 mg PO once daily; titrate to 10 mg/d (1) · Heart failure: 3.125 mg PO BID, doubling every 2 weeks as tolerated to target 25 mg BID (50 mg BID if >85 kg). Hypertension: 6.25 mg PO BID, titrate to 25 mg BID (1)

2.5, 5, 10 mg tablets; 1 mg/mL oral suspension (1) · IR tablets 3.125, 6.25, 12.5, 25 mg; Coreg CR capsules 10, 20, 40, 80 mg (once-daily) (1)

Oral (2)

Antihypertensive effect within 1 week; heart-failure mortality benefit accrues over months of titration (1) · BP effect within 24 hours; full effect at 1-2 weeks (long half-life) (1)

24 hours (1) · ~12 hours (IR); 24 hours (CR) (1)

30-50 hours'"`UNIQ--ref-00000078-QINU`"' (1) · 7-10 hours'"`UNIQ--ref-0000001B-QINU`"' (1)

64-90% (oral; not affected by food)'"`UNIQ--ref-00000079-QINU`"' (1) · ~25-35% (extensive first-pass), increased by food which slows absorption and reduces orthostatic risk'"`UNIQ--ref-0000001C-QINU`"' (1)

Limited data; case series and registries suggest no major teratogenicity but other antihypertensives (labetalol, nifedipine) are typically preferred.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) · Limited human data; β-blocker class effects include fetal growth restriction and neonatal bradycardia/hypoglycemia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

[[USLegal:Prescription only|Rx-only]] in US (2)

Showing below up to 2 results in range #1 to #2.

A

Amlodipine

C

Carvedilol

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"