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Medicines > classes: [[:Category:Antispastics|Antispastic]] & duration: 4-6 hours (oral, TID-QID dosing)

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generic:
Baclofen (1)
brand:
Lioresal (oral, intrathecal pump), Ozobax / Fleqsuvy (oral suspension), Gablofen (intrathecal), Lyvispah (oral granules) (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"' (1)
starting dose:
Oral: 5 mg PO TID, titrate by 5 mg per dose every 3 days. Intrathecal: bolus test dose, then continuous infusion via implanted pump (1)
preparations:
Tablets 5, 10, 20 mg; oral suspension 5 mg/5 mL (Ozobax, Fleqsuvy); intrathecal injection 50, 500, 1000, 2000 mcg/mL (Lioresal Intrathecal, Gablofen); oral granules (Lyvispah) (1)
fda max:
80 mg/day oral (higher off-label) (1)
routes:
intrathecal (via implanted infusion pump) (1) · Oral (1)
onset:
1-2 hours (oral) (1)
duration: (Click arrow to add another value)
halflife:
3-4 hours'"`UNIQ--ref-00000026-QINU`"' (1)
bioavailability:
~70-85% (oral)'"`UNIQ--ref-00000027-QINU`"' (1)
pregnancy:
Limited human data.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US. Not a controlled substance'"`UNIQ--ref-00000028-QINU`"' (1)

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