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Medicines (732)

Medicines > classes: [[:Category:Biguanides|Biguanide]]

& duration

: ~12 hours (IR); 24 hours (ER)

or ~7-8 hours

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Metformin (1)

Glucophage, Glucophage XR, Fortamet, Glumetza, Riomet (1)

'"`UNIQ--vote-00000013-QINU`"' Does not stimulate insulin secretion; minimal hypoglycemia risk as monotherapy. Cleared renally unchanged; dose-adjust by eGFR'"`UNIQ--ref-00000014-QINU`"'. Rare lactic acidosis primarily in renal failure or acute illness. (1)

'"`UNIQ--vote-00000015-QINU`"', '"`UNIQ--vote-00000016-QINU`"', '"`UNIQ--vote-00000017-QINU`"' (1)

500 mg PO once or twice daily with meals; titrate weekly to limit GI effects (1)

500 mg, 850 mg, 1000 mg IR tablets; 500 mg, 750 mg, 1000 mg ER tablets; 500 mg/5 mL oral solution (1)

2550 mg/d (IR); 2000 mg/d (ER) (1)

Oral (1)

Glucose lowering within days; HbA1c effect at 8-12 weeks (1)

6.2 hours (plasma); ~17 hours in erythrocytes'"`UNIQ--ref-00000018-QINU`"' (1)

50-60% (oral; decreased with food, but food given anyway for GI tolerance)'"`UNIQ--ref-00000019-QINU`"' (1)

Generally considered safe; widely used in PCOS and gestational diabetes; placental transfer occurs.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

[[USLegal:Prescription only|Rx-only]] in US (1)

Showing below up to 1 result in range #1 to #1.

M

Metformin

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