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Medicines > classes: [[:Category:Bowel_preparation_agents|Bowel preparation agent]] & duration: Hours

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generic:
Polyethylene glycol 3350 (PEG 3350) (1)
brand:
MiraLAX (OTC), GlycoLax, GoLYTELY (with electrolytes for bowel prep), CoLyte, MoviPrep, NuLYTELY (1)
classes: (Click arrow to add another value)
mechanism:
'"`UNIQ--vote-0000132D-QINU`"' Electrolyte-balanced bowel-prep formulations are designed to be iso-osmotic with plasma so the volume passes through without net fluid or electrolyte shifts, the basis of their safety for whole-bowel evacuation. (1)
uses:
'"`UNIQ--vote-0000132E-QINU`"', '"`UNIQ--vote-0000132F-QINU`"', '"`UNIQ--vote-00001330-QINU`"' (1)
starting dose:
Constipation: 17 g (one capful) PO daily dissolved in 4-8 oz fluid; bowel prep: 4 L of PEG-electrolyte solution split-dose evening before and morning of procedure (1)
preparations:
17 g (OTC) and 14 g (Rx) powder packets; 238, 510, 527 g bottles; PEG-electrolyte preparations 4 L (GoLYTELY, NuLYTELY) (1)
fda max:
Indication-specific; bowel prep regimens reach 4 L cumulative (1)
routes:
Oral (1)
onset:
Constipation: 1-3 days; bowel prep: 1-3 hours after starting (1)
duration: (Click arrow to add another value)
halflife:
Not meaningfully described (negligible systemic absorption) (1)
bioavailability:
<0.1% systemic absorption (PEG 3350 is too large to absorb intact) (1)
pregnancy:
Generally considered safe due to minimal systemic absorption.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
OTC (MiraLAX) and [[USLegal:Prescription only|Rx-only]] (electrolyte solutions for bowel prep) in US (1)

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