Jump to content

Drilldown: Medicines

Choose a table:


Medicines > classes: [[:Category:Classical Psychedelics (Serotonergic)|Serotonergic psychedelic]] & duration: 4-6 hours & pregnancy: Not studied in human pregnancy; no approved clinical use in any population

Use the filters below to narrow your results.

generic:
Psilocybin (1)
brand:
COMP360 (Compass Pathways, investigational synthesized clinical formulation) (1)
classes: (Click arrow to add another value)
mechanism:
Prodrug to [[Psilocin|psilocin]] (4-hydroxy-N,N-dimethyltryptamine), a partial agonist at the [[Receptor:5-HT2A|5-HT2A]] serotonin receptor; the action that defines the classical-psychedelic mechanism (1)
uses:
(investigational) '"`UNIQ--vote-000000EF-QINU`"', '"`UNIQ--vote-000000F0-QINU`"', '"`UNIQ--vote-000000F1-QINU`"', '"`UNIQ--vote-000000F2-QINU`"', '"`UNIQ--vote-000000F3-QINU`"' (1)
starting dose:
Modern clinical-trial standard: 25 mg synthesized psilocybin, single oral dose with psychological support (1)
preparations:
Synthesized psilocybin capsules (COMP360 and other investigational formulations); dried whole [[Psilocybe|Psilocybe]] mushrooms (variable potency, no legal supply chain in most jurisdictions); psilocybin truffles (Psilocybe sclerotia, legal in the Netherlands) (1)
fda max:
Not FDA-approved; clinical-trial protocols use up to 30 mg in adult investigational dosing (1)
routes:
Oral (1)
onset:
20-45 min subjective onset; psilocin formation from psilocybin requires intestinal and hepatic alkaline phosphatase (1)
duration: (Click arrow to add another value)
halflife:
Psilocin: ~2-3 h; psilocybin itself is a prodrug, dephosphorylated within minutes of absorption (1)
bioavailability:
Oral bioavailability of psilocin from administered psilocybin approximately 50% (1)
pregnancy: (Click arrow to add another value)
legal:
None (1)

Showing below up to 1 result in range #1 to #1.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"