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Drilldown: Medicines

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Medicines > classes: [[:Category:Eugeroics|Eugeroic]] & fda max: 400 mg/day.'"`UNIQ--ref-0000006C-QINU`"'

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generic:
Modafinil (1)
brand:
Provigil (Teva/Cephalon); Alertec (Canada); Modavigil (Australia) (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
None (1)
starting dose:
None (1)
preparations:
Tablets: 100 mg, 200 mg (scored). [[Armodafinil]] (Nuvigil), the R-enantiomer of modafinil, is available separately as 50 mg, 150 mg, 200 mg, and 250 mg tablets. (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
Peak plasma concentration in 2-4 hours after oral administration. Clinically perceptible wakefulness-promoting effects typically begin within 1-2 hours of dosing.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
duration:
Effective duration approximately 12-15 hours at the 200 mg dose, consistent with the elimination half-life. A single morning dose generally sustains wakefulness throughout the day without substantially disrupting nighttime sleep onset when taken early.'"`UNIQ--ref-0000006D-QINU`"' (1)
halflife:
None (1)
bioavailability:
Oral bioavailability is not precisely established in the label but absorption is rapid and essentially complete. Food delays peak plasma concentration by approximately one hour but does not reduce the extent of absorption.'"`UNIQ--ref-0000006F-QINU`"' (1)
pregnancy:
None (1)
legal:
None (1)
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