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Drilldown: Medicines

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Medicines (732)

Medicines > classes: [[:Category:Fixed-dose_combinations|Fixed-dose combination]]

& fda max: Acetaminophen 4 g/d absolute (3 g/d conservative); oxycodone titrated to effect

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Oxycodone / Acetaminophen (1)

Percocet, Endocet, Roxicet, Tylox, Primlev (1)

'"`UNIQ--vote-000014DD-QINU`"' The combination is the most-prescribed opioid analgesic in the US for moderate-to-severe acute pain. CPIC PGx guidance addresses CYP2D6-driven exposure variation'"`UNIQ--ref-000014DE-QINU`"'. (1)

'"`UNIQ--vote-000014DF-QINU`"', '"`UNIQ--vote-000014E0-QINU`"', '"`UNIQ--vote-000014E1-QINU`"' (1)

5 mg / 325 mg PO every 4-6 hours as needed; total acetaminophen <3 g/d (1)

Oxycodone/acetaminophen 2.5/325, 5/325, 7.5/325, 10/325 mg tablets; 5/325 mg/5 mL solution (1)

Oral (1)

10-30 minutes (1)

4-6 hours (1)

Oxycodone 3-5 hours; acetaminophen 1-3 hours'"`UNIQ--ref-000014E2-QINU`"' (1)

~60-87% oxycodone (high and predictable, less CYP-genotype-dependent than codeine or hydrocodone); 85-98% acetaminophen'"`UNIQ--ref-000014E3-QINU`"' (1)

Limited use in pregnancy; chronic third-trimester opioid exposure produces neonatal opioid withdrawal syndrome and respiratory depression at delivery.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

[[USLegal:Schedule II|Schedule II controlled substance]] in US. Acetaminophen content limited to ≤325 mg per dosage unit (FDA 2014) (1)

Showing below up to 1 result in range #1 to #1.

P

Percocet

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