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Medicines > classes: [[:Category:Hormone_replacement|Hormone replacement]] & onset: Hours (faster than T4); peak biologic activity 24-48 hours

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generic:
Liothyronine (T3, triiodothyronine sodium) (1)
brand:
Cytomel (oral), Triostat (IV) (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000149A-QINU`"', '"`UNIQ--vote-0000149B-QINU`"', '"`UNIQ--vote-0000149C-QINU`"' (1)
starting dose:
Hypothyroidism: 5-25 mcg PO daily (start low, titrate slowly); myxedema coma: 5-20 mcg IV q4-12h with T4 loading (1)
preparations:
5, 25, 50 mcg tablets (Cytomel); 10 mcg/mL IV (Triostat) (1)
fda max:
100 mcg/d typical (1)
routes:
IV (1) · Oral (1)
onset: (Click arrow to add another value)
duration:
24-72 hours (1)
halflife:
~1 day (much shorter than T4's ~7 days)'"`UNIQ--ref-0000149D-QINU`"' (1)
bioavailability:
~95% (oral)'"`UNIQ--ref-0000149E-QINU`"' (1)
pregnancy:
T4 (levothyroxine) is the first-line in pregnancy; T3 is rarely needed.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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