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Medicines (732)

Medicines > classes: [[:Category:Incretin_modulators|Incretin pathway modulator]]

& fda max: 100 mg/d

& routes: Oral

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Sitagliptin (1)

Januvia; with metformin Janumet/Janumet XR (1)

'"`UNIQ--vote-00000762-QINU`"' Largely renally cleared, hence the eGFR-tiered dosing. Rare but well-documented signals: acute pancreatitis (uncertain causal contribution), severe joint pain, and bullous pemphigoid (class effect, especially in older Asian patients)'"`UNIQ--ref-00000763-QINU`"'. (1)

'"`UNIQ--vote-00000764-QINU`"' (1)

100 mg PO once daily (50 mg if CrCl 30-44; 25 mg if <30 or dialysis) (1)

25, 50, 100 mg tablets; combination tablets with metformin (1)

Postprandial glucose effect within days; HbA1c by 12 weeks (1)

24 hours (1)

~12.4 hours'"`UNIQ--ref-00000765-QINU`"' (1)

~87% (oral)'"`UNIQ--ref-00000766-QINU`"' (1)

Limited data; switch to insulin where feasible.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

[[USLegal:Prescription only|Rx-only]] in US (1)

Showing below up to 1 result in range #1 to #1.

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Sitagliptin

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