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Medicines > classes: [[:Category:Macrocyclic_lactones|Macrocyclic lactone (avermectin)]] & duration : 8-12 hours or Variable

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generic:
Ivermectin (1)
brand:
Stromectol (oral, generic), Sklice (lice, topical), Soolantra (rosacea, topical 1%) (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000108C-QINU`"', '"`UNIQ--vote-0000108D-QINU`"', '"`UNIQ--vote-0000108E-QINU`"', '"`UNIQ--vote-0000108F-QINU`"', '"`UNIQ--vote-00001090-QINU`"', '"`UNIQ--vote-00001091-QINU`"' (1)
starting dose:
Strongyloides 200 mcg/kg PO single dose; scabies 200 mcg/kg PO repeated at 7-14 days; onchocerciasis 150 mcg/kg q6-12 months (1)
preparations:
3 mg tablets (Stromectol); 0.5% topical lotion (Sklice); 1% topical cream (Soolantra) (1)
fda max:
Single 200-400 mcg/kg per dose for systemic indications (1)
routes:
Oral (1) · topical (1)
onset:
Hours to days (1)
duration: (Click arrow to add another value)
halflife:
~16-18 hours'"`UNIQ--ref-00001092-QINU`"' (1)
bioavailability:
~60% (oral; substantially increased with high-fat meal)'"`UNIQ--ref-00001093-QINU`"' (1)
pregnancy:
Limited data; risk-benefit case by case; pregnancy is not a strict contraindication in WHO mass drug administration programs.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (the veterinary preparations are not for human use) (1)

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