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Medicines > classes: [[:Category:Mast_cell_stabilizers|Mast cell stabilizer]] & fda max: Once daily (Pataday 0.7%); BID (other ophthalmic)

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generic:
Olopatadine (1)
brand:
Patanol, Pataday (ophthalmic, now OTC), Patanase (intranasal) (1)
classes: (Click arrow to add another value)
mechanism:
'"`UNIQ--vote-000011D5-QINU`"' Minimal systemic absorption and the dual mechanism underlie its first-line role in seasonal allergic conjunctivitis. Comfort drops without preservatives are available for sensitive patients'"`UNIQ--ref-000011D6-QINU`"'. (1)
uses:
'"`UNIQ--vote-000011D7-QINU`"', '"`UNIQ--vote-000011D8-QINU`"' (1)
starting dose:
Ophthalmic Pataday 0.7%: 1 drop in each eye once daily (24-hour formulation); Patanol 0.1% BID; intranasal Patanase 2 sprays/nostril BID (1)
preparations:
0.1% (Patanol), 0.2% (Pataday once-daily original), 0.7% (Pataday 24-hour) ophthalmic solutions; 0.6% nasal spray (1)
fda max: (Click arrow to add another value)
routes:
intranasal (1) · Topical ophthalmic (1)
onset:
Symptom relief within 30-60 minutes (1)
duration:
24 hours (0.7% formulation); 8-12 hours (lower-strength) (1)
halflife:
~3 hours (systemic, when measurable; topical action dominates)'"`UNIQ--ref-000011D9-QINU`"' (1)
bioavailability:
Topical with minimal systemic absorption'"`UNIQ--ref-000011DA-QINU`"' (1)
pregnancy:
Generally considered safe; minimal systemic exposure.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
OTC (Pataday ophthalmic) and [[USLegal:Prescription only|Rx-only]] (Patanase intranasal) in US (1)

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