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Choose a table:
Medicines (732)
Medicines
> classes:
[[:Category:Mood stabilizers|Mood stabilizer]]
&
preparations:
None
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Research material
·
Classic Psychedelic
·
Stimulant
·
Opioid
·
Sedative-Hypnotic
·
Phenethylamine
·
Tryptamine
·
Benzodiazepine
·
Botanical
·
[[:Category:Antihypertensives|Antihypertensive]]
·
Dissociative
·
Anticonvulsant
·
Antidepressant
·
Plant Medicine
·
Analgesic
·
Antiparkinsonian
·
Antipsychotic
·
Empathogen
·
Neuroleptic
·
Cathinone
Other values:
2C-x series
5HT1A activity than aripiprazole
5HT2A
5HT2A/D2 antagonist with proposed differential pre/post-synaptic D2 activity
AChE inhibitor
APL)]]
Addiction medicine
Alpha-1 Adrenergic Antagonist
Alpha-2 agonist
Amphetamine
Amphetamine-like
Analgesic / antipyretic
Androgen / Anabolic Steroid
Anesthetic
Anesthetic adjunct
Animal Medicine
Anti-CGRP ligand monoclonal antibody
Anti-CGRP receptor monoclonal antibody
Anti-amyloid beta (Aβ) monoclonal antibody
Anti-dementia
Anticholinergic
Antiemetic
Antihistamine
Anxiolytic
Atypical antipsychotic
Barbiturate
Benzofuran
Beta blocker
CGRP receptor antagonist
CNS stimulant
COMT inhibitor
Caffeine plant
Cannabinoid
Cannabinoid (minor)
Cardioselective (β1)
Cardioselective (β1) + vasodilator
Cathinone source
Combined cholinesterase inhibitor + NMDA antagonist
D2/5HT1A partial agonist with stronger α1A
D2/D3/5HT1A partial agonist
Daimonica
Decongestant
Deliriant
Designer benzodiazepine
Dopamine agonist
Dual orexin receptor antagonist (DORA)
Empathogenica
Ergoline
Ergotamine
Eugeroic
Excitantia
GABA-A positive allosteric modulator
GABA-A positive allosteric modulator (oral)
GABAB Agonist; Endogenous GHB receptor agonist
GABAergic
GLP-1 receptor agonist
Gepant
Histamine H3 receptor inverse agonist / antagonist
Inhalant
Inhalational anesthetic
Local anesthetic
Lysergamide
MAO-B inhibitor
MAOI
Migraine medicine
Mood Stabilizer
Multimodal antidepressant: SERT inhibitor + 5HT1A agonist + 5HT1B partial agonist + 5HT3/5HT7 antagonist
Multimodal serotonergic; HSDD treatment
Muscle relaxant
NDRI
NMDA receptor antagonist (uncompetitive
NMDA receptor antagonist (uncompetitive)
NMDA receptor antagonist + sigma-1 agonist + NDRI (combination)
NRI
NSAID
Neuroactive steroid
Neuromuscular blocker
Neurotoxin
Non-selective
Nootropic
Norepinephrine-dopamine reuptake inhibitor (NDRI)
Oneirogen
Opioid agonist therapy (OAT); Partial μ-agonist + abuse-deterrent
Opioid antagonist
PDE5 Inhibitor
Peptide
Phantastica
Pharmaceutical
Phenidate
Piperazine
Plant Med
Prodrug
Psychedelic
Psychostimulant
Pyrrolidinophenone
RIMA
Racetam
Rhapsodica
SARI
SNRI
SSRI
SSRI)]]
Sedative
Selective 5HT2A inverse agonist (with weaker 5HT2C inverse agonism)
Selective norepinephrine reuptake inhibitor (NRI) with 5HT1A partial agonism
Serotonin partial agonist reuptake inhibitor (SPARI)
Synthetic cannabinoid
TCA
THC oxidation product
Thienodiazepine
Trace amine
Triazolobenzodiazepine
Triptan
Tropane alkaloid plant
Typical antipsychotic
Xanthine
Z-drug
[[:Category:5-HT3_antagonists|5-HT3 receptor antagonist]]
[[:Category:5-alpha-reductase_inhibitors|5α-reductase inhibitor (dual type I/II)]]
[[:Category:5-alpha-reductase_inhibitors|5α-reductase inhibitor]]
[[:Category:5-aminosalicylates|5-aminosalicylate (5-ASA)]]
[[:Category:ACE_inhibitors|ACE inhibitor]]
[[:Category:ADHD medicines|ADHD medicine]]
[[:Category:AUD medicines|Alcohol use disorder medicine]]
[[:Category:Acetic_acid_derivatives|Acetic acid derivative]]
[[:Category:Acetylcholinesterase inhibitors|Acetylcholinesterase inhibitor]]
[[:Category:Adamantanes|Adamantane derivative]]
[[:Category:Aldosterone_antagonists|Mineralocorticoid (aldosterone) receptor antagonist]]
[[:Category:Allylamines|Allylamine]]
[[:Category:Alpha-1_blockers|Alpha-1 adrenergic blocker (non-selective)]]
[[:Category:Alpha-1_blockers|Alpha-1A adrenergic blocker]]
[[:Category:Alpha-2 adrenergic agonists|Alpha-2 adrenergic agonist]]
[[:Category:Alpha-2_agonists|Alpha-2 adrenergic agonist]]
[[:Category:Aminoglycosides|Aminoglycoside antibiotic]]
[[:Category:Aminopenicillins|Aminopenicillin]]
[[:Category:Amphetamines|Amphetamine]]
[[:Category:Analgesics|Analgesic (opioid-sparing parenteral)]]
[[:Category:Analgesics|Analgesic]]
[[:Category:Analgesics|Non-opioid analgesic]]
[[:Category:Androgen_modulators|Androgen modulator]]
[[:Category:Anesthetics|Anesthetic (historical)]]
[[:Category:Anesthetics|Anesthetic]]
[[:Category:Angiotensin_receptor_blockers|Angiotensin receptor blocker (ARB)]]
[[:Category:Anorectics|Anorectic (appetite suppressant)]]
[[:Category:Anorectics|Anorectic (weight-loss agent)]]
[[:Category:Antacids|Antacid (carbonate)]]
[[:Category:Antacids|Antacid (hydroxide)]]
[[:Category:Antacids|Antacid]]
[[:Category:Anti-dementia medicines|Anti-dementia medicine]]
[[:Category:Anti-herpesvirus_agents|Anti-herpesvirus agent]]
[[:Category:Anti-inflammatories|Anti-inflammatory]]
[[:Category:Anti-influenza_agents|Anti-influenza agent]]
[[:Category:Anti-ulcer_agents|Anti-ulcer agent]]
[[:Category:Antiandrogens|Antiandrogen]]
[[:Category:Antianginals|Antianginal]]
[[:Category:Antiarrhythmics|Antiarrhythmic (IV sulfate
[[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan Williams Class IB)]]
[[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan-Williams class IC)]]
[[:Category:Antiarrhythmics|Antiarrhythmic (Vaughan-Williams class III)]]
[[:Category:Antiarrhythmics|Antiarrhythmic (class IV)]]
[[:Category:Antiasthmatic_agents|Antiasthmatic]]
[[:Category:Antibacterials|Antibacterial (anaerobic)]]
[[:Category:Antibacterials|Antibacterial]]
[[:Category:Anticaries_agents|Anticaries agent]]
[[:Category:Anticholinergics|Anticholinergic]]
[[:Category:Anticoagulants|Anticoagulant]]
[[:Category:Anticonvulsants|Anticonvulsant]]
[[:Category:Antidepressants|Antidepressant (bupropion
[[:Category:Antidepressants|Antidepressant (fluoxetine
[[:Category:Antidepressants|Antidepressant]]
[[:Category:Antidiarrheals|Antidiarrheal]]
[[:Category:Antiemetics|Antiemetic]]
[[:Category:Antiepileptics|Antiepileptic]]
[[:Category:Antifolates|Antifolate]]
[[:Category:Antifungals|Antifungal (allylamine)]]
[[:Category:Antifungals|Antifungal (imidazole)]]
[[:Category:Antifungals|Antifungal (triazole)]]
[[:Category:Antifungals|Antifungal]]
[[:Category:Antiglaucoma medicines|Antiglaucoma medicine]]
[[:Category:Antigout_agents|Antigout agent]]
[[:Category:Antihistamines|Antihistamine (potent H1)]]
[[:Category:Antihistamines|Antihistamine]]
[[:Category:Antihistamines|First-generation antihistamine (ethanolamine)]]
[[:Category:Antihistamines|First-generation antihistamine (piperazine)]]
[[:Category:Antihistamines|First-generation antihistamine]]
[[:Category:Antihyperglycemic_agents|Antihyperglycemic agent]]
[[:Category:Antihypertensives|Antihypertensive (historical)]]
[[:Category:Antihyperuricemic_agents|Antihyperuricemic agent]]
[[:Category:Antimalarials|Antimalarial (4-aminoquinoline)]]
[[:Category:Antimanic medicines|Antimanic]]
[[:Category:Antimetabolites|Antimetabolite (pyrimidine analog)]]
[[:Category:Antimigraine medicines|Antimigraine medicine]]
[[:Category:Antimigraine_agents|Antimigraine agent]]
[[:Category:Antimuscarinics|Antimuscarinic (M3-selective)]]
[[:Category:Antimuscarinics|Antimuscarinic]]
[[:Category:Antineoplastics|Antineoplastic (oral
[[:Category:Antineoplastics|Antineoplastic]]
[[:Category:Antioxidants|Antioxidant]]
[[:Category:Antiparasitics|Antiparasitic]]
[[:Category:Antiparkinsonians|Antiparkinsonian]]
[[:Category:Antiplatelet_agents|Antiplatelet agent]]
[[:Category:Antiplatelets|Antiplatelet]]
[[:Category:Antiprotozoals|Antiprotozoal]]
[[:Category:Antipruritics|Antipruritic]]
[[:Category:Antipyretics|Antipyretic]]
[[:Category:Antiresorptives|Antiresorptive]]
[[:Category:Antisecretory_agents|Gastric acid suppressant]]
[[:Category:Antiseptics|Antiseptic]]
[[:Category:Antispasmodics|GI antispasmodic]]
[[:Category:Antispastics|Antispastic]]
[[:Category:Antithyroid_agents|Antithyroid agent]]
[[:Category:Antitussives|Antitussive]]
[[:Category:Antivertigo medicines|Antivertigo medicine]]
[[:Category:Antivirals|Antiviral]]
[[:Category:Anxiolytics|Anxiolytic]]
[[:Category:Aromatase_inhibitors|Aromatase inhibitor (non-steroidal)]]
[[:Category:Arylcyclohexylamines|Arylcyclohexylamine]]
[[:Category:Atypical neuroleptics|Atypical neuroleptic (second-generation)]]
[[:Category:Atypical neuroleptics|Atypical neuroleptic]]
[[:Category:Azalides|Azalide]]
[[:Category:Azapirones|Azapirone]]
[[:Category:Azo_dyes|Azo dye]]
[[:Category:B-vitamins|B-vitamin]]
[[:Category:BPH_treatments|Benign prostatic hyperplasia treatment]]
[[:Category:Bacteriostatic_antibiotics|Bacteriostatic antibiotic]]
[[:Category:Barbiturates|Barbiturate (butalbital)]]
[[:Category:Barbiturates|Barbiturate (parent compound)]]
[[:Category:Basal_insulins|Basal insulin]]
[[:Category:Benzisoxazoles|Benzisoxazole]]
[[:Category:Benzodiazepines|Benzodiazepine (long-acting)]]
[[:Category:Benzodiazepines|Benzodiazepine]]
[[:Category:Beta blockers|Beta blocker (cardioselective β1)]]
[[:Category:Beta blockers|Beta blocker (non-selective
[[:Category:Beta blockers|Beta blocker (non-selective)]]
[[:Category:Beta blockers|Combined alpha-1 and non-selective beta blocker]]
[[:Category:Beta-2_adrenergic_agonists|Short-acting β2-agonist]]
[[:Category:Beta-3_agonists|β3 adrenergic agonist]]
[[:Category:Beta-lactam_antibiotics|β-lactam antibiotic]]
[[:Category:Biguanides|Biguanide]]
[[:Category:Biologics|Biologic]]
[[:Category:Bisbiguanides|Bisbiguanide]]
[[:Category:Bisphosphonates|Bisphosphonate (nitrogen-containing)]]
[[:Category:Bowel_preparation_agents|Bowel preparation agent]]
[[:Category:Bronchodilators|Bronchodilator]]
[[:Category:Calcineurin_inhibitors|Calcineurin inhibitor]]
[[:Category:Calcium_channel_blockers|Calcium channel blocker (dihydropyridine)]]
[[:Category:Calcium_channel_blockers|Calcium channel blocker (non-dihydropyridine)]]
[[:Category:Calcium_channel_blockers|Calcium channel blocker]]
[[:Category:Calcium_supplements|Calcium supplement]]
[[:Category:Carbonic_anhydrase_inhibitors|Carbonic anhydrase inhibitor (topical)]]
[[:Category:Cardiovascular_agents|Cardiovascular agent]]
[[:Category:Catecholamines|Catecholamine]]
[[:Category:Cephalosporins|Cephalosporin (first-generation)]]
[[:Category:Cephalosporins|Cephalosporin (second-generation)]]
[[:Category:Cephalosporins|Cephalosporin (third-generation)]]
[[:Category:Cholesterol_absorption_inhibitors|Cholesterol absorption inhibitor]]
[[:Category:Chronobiotics|Chronobiotic (circadian phase regulator)]]
[[:Category:Classical Psychedelics (Serotonergic)|Classic Psychedelic]]
[[:Category:Classical Psychedelics (Serotonergic)|Serotonergic psychedelic]]
[[:Category:Corticosteroids|Corticosteroid]]
[[:Category:Crystalloid_IV_fluids|Crystalloid IV fluid]]
[[:Category:Cyclopentyltriazolopyrimidines|Cyclopentyltriazolopyrimidine]]
[[:Category:DMARDs|DMARD]]
[[:Category:DOACs|Direct oral anticoagulant (DOAC)]]
[[:Category:DPP-4_inhibitors|DPP-4 inhibitor]]
[[:Category:Decongestants|Decongestant]]
[[:Category:Depigmenting_agents|Depigmenting agent]]
[[:Category:Dibenzothiazepines|Dibenzothiazepine]]
[[:Category:Diphenylmethane_laxatives|Diphenylmethane laxative]]
[[:Category:Direct_factor_Xa_inhibitors|Direct factor Xa inhibitor]]
[[:Category:Direct_vasodilators|Direct arteriolar vasodilator]]
[[:Category:Disaccharides|Non-absorbable disaccharide]]
[[:Category:Dissociatives|Dissociative]]
[[:Category:Diuretics|Diuretic]]
[[:Category:Dopamine agonists|Dopamine D2/D3 receptor agonist (non-ergot)]]
[[:Category:Dopamine_D2_antagonists|Dopamine D2 antagonist]]
[[:Category:Electrolyte_replacements|Electrolyte replacement]]
[[:Category:Endocrine_therapy|Endocrine therapy]]
[[:Category:Estrogens|Estrogen]]
[[:Category:Eugeroics|Eugeroic]]
[[:Category:Expectorants|Expectorant]]
[[:Category:Fat-soluble_vitamins|Fat-soluble vitamin]]
[[:Category:Fibrates|Fibrate]]
[[:Category:Fixed-dose_combinations|Fixed-dose combination]]
[[:Category:Fluoroquinolones|Fluoroquinolone antibiotic]]
[[:Category:GABA-B receptor agonists|GABA-B receptor agonist]]
[[:Category:Gabapentinoids|Gabapentinoid]]
[[:Category:Gepants|Gepant (small-molecule CGRP receptor antagonist)]]
[[:Category:Glaucoma_medications|Glaucoma medication]]
[[:Category:Glucocorticoids|Glucocorticoid (intermediate-acting)]]
[[:Category:Glucocorticoids|Glucocorticoid (long-acting
[[:Category:Glucocorticoids|Glucocorticoid (short-acting
[[:Category:Glucocorticoids|Glucocorticoid]]
[[:Category:Guanylate_cyclase_C_agonists|Guanylate cyclase-C agonist]]
[[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist (second-generation)]]
[[:Category:H1_receptor_antagonists|Histamine H1 receptor antagonist]]
[[:Category:H2_receptor_antagonists|Histamine H2 receptor antagonist]]
[[:Category:Heart failure medicines|Heart failure medicine]]
[[:Category:Heart_failure_medications|Heart failure medication]]
[[:Category:Hematinics|Hematinic]]
[[:Category:Hepatic_encephalopathy_treatments|Hepatic encephalopathy treatment]]
[[:Category:Hormonal_contraceptives|Hormonal contraceptive (Depo)]]
[[:Category:Hormonal_contraceptives|Hormonal contraceptive]]
[[:Category:Hormone_replacement_therapy|Hormone replacement therapy]]
[[:Category:Hormone_replacement|Hormone replacement]]
[[:Category:Hormones|Hormone (steroid)]]
[[:Category:Hydroxypyridones|Hydroxypyridone]]
[[:Category:IBD_medications|IBD medication]]
[[:Category:IBS_treatments|IBS-C treatment]]
[[:Category:Immunomodulators|Immunomodulator]]
[[:Category:Immunosuppressants|Immunosuppressant]]
[[:Category:Incretin_modulators|Incretin pathway modulator]]
[[:Category:Inhaled_corticosteroids|Inhaled corticosteroid (ICS)]]
[[:Category:Inotropes|Inotrope]]
[[:Category:Insulin_secretagogues|Insulin secretagogue]]
[[:Category:Insulins|Insulin]]
[[:Category:Intranasal_antihistamines|Intranasal antihistamine]]
[[:Category:Iron_supplements|Iron supplement]]
[[:Category:Leukotriene_receptor_antagonists|Leukotriene receptor antagonist]]
[[:Category:Lincosamides|Lincosamide antibiotic]]
[[:Category:Lipid-lowering_agents|Lipid-lowering agent]]
[[:Category:Local anesthetics|Local anesthetic (amide class)]]
[[:Category:Long-acting_insulins|Long-acting insulin analog]]
[[:Category:Long-acting_muscarinic_antagonists|Long-acting muscarinic antagonist (LAMA)]]
[[:Category:Loop_diuretics|Loop diuretic]]
[[:Category:Macrocyclic_lactones|Macrocyclic lactone (avermectin)]]
[[:Category:Macrolide_antibiotics|Macrolide antibiotic]]
[[:Category:Mast_cell_stabilizers|Mast cell stabilizer]]
[[:Category:Mealtime_insulins|Mealtime (bolus) insulin]]
[[:Category:Melatonin receptor agonists|Melatonin receptor agonist]]
[[:Category:Methylxanthines|Methylxanthine (caffeine)]]
[[:Category:Microtubule_inhibitors|Microtubule inhibitor]]
[[:Category:Migraine prophylactics|Migraine prophylactic]]
[[:Category:Migraine_prophylaxis|Migraine prophylaxis]]
[[:Category:Monoclonal_antibodies|Monoclonal antibody (fully human IgG1)]]
[[:Category:Monoclonal_antibodies|Monoclonal antibody (fully human IgG2)]]
[[:Category:Mood stabilizers|Mood stabilizer (off-label)]]
[[:Category:Mood stabilizers|Mood stabilizer]]
[[:Category:Mood_stabilizers|Mood stabilizer]]
[[:Category:Mucolytics|Mucolytic]]
[[:Category:Mucosal_protectants|Mucosal protectant]]
[[:Category:NDRIs|Norepinephrine-dopamine reuptake inhibitor (NDRI)]]
[[:Category:NMDA antagonists|NMDA receptor antagonist]]
[[:Category:NMDA receptor antagonists|NMDA receptor antagonist (uncompetitive
[[:Category:NMDA_receptor_antagonists|NMDA receptor antagonist]]
[[:Category:NRIs|Selective norepinephrine reuptake inhibitor (NRI)]]
[[:Category:NSAIDs|NSAID (aspirin)]]
[[:Category:NSAIDs|NSAID (naproxen)]]
[[:Category:NSAIDs|Non-steroidal anti-inflammatory (NSAID
[[:Category:NSAIDs|Non-steroidal anti-inflammatory (NSAID)]]
[[:Category:NSAIDs|Non-steroidal anti-inflammatory drug (NSAID)]]
[[:Category:Neuraminidase_inhibitors|Neuraminidase inhibitor]]
[[:Category:Neuroleptics|Atypical neuroleptic (olanzapine)]]
[[:Category:Neuroleptics|Neuroleptic]]
[[:Category:Neuropathic pain medicines|Neuropathic pain medicine]]
[[:Category:Nitrates|Organic nitrate]]
[[:Category:Nitrofurans|Nitrofuran]]
[[:Category:Nitroimidazoles|Nitroimidazole antibiotic]]
[[:Category:Non-benzodiazepine hypnotics|Non-benzodiazepine hypnotic]]
[[:Category:Non-opioid_analgesics|Non-opioid analgesic (acetaminophen)]]
[[:Category:Nucleoside_analogs|Nucleoside analog (prodrug)]]
[[:Category:Nucleoside_analogs|Nucleoside analog]]
[[:Category:OUD medicines|Opioid use disorder medicine]]
[[:Category:Ocular_hypotensive_agents|Ocular hypotensive agent]]
[[:Category:Omega-3_fatty_acids|Omega-3 fatty acid]]
[[:Category:Ophthalmic_antihistamines|Ophthalmic antihistamine]]
[[:Category:Opioid analgesics|Opioid analgesic (atypical
[[:Category:Opioid analgesics|Opioid analgesic (full mu-agonist)]]
[[:Category:Opioid analgesics|Opioid analgesic (natural phenanthrene from opium poppy)]]
[[:Category:Opioid analgesics|Opioid analgesic (partial mu-agonist
[[:Category:Opioid analgesics|Opioid analgesic (semi-synthetic)]]
[[:Category:Opioid antagonists|Opioid antagonist (mu and kappa)]]
[[:Category:Opioid withdrawal medicines|Opioid withdrawal medicine]]
[[:Category:Opioid_analgesics|Opioid analgesic (codeine
[[:Category:Opioid_analgesics|Opioid analgesic]]
[[:Category:Opioid_antagonists|Opioid antagonist (naltrexone)]]
[[:Category:Opioid_receptor_agonists|Peripheral opioid receptor agonist (μ-selective
[[:Category:Orexigenics|Appetite-promoting medicine (orexigenic)]]
[[:Category:Osmotic_laxatives|Osmotic laxative (citrate
[[:Category:Osmotic_laxatives|Osmotic laxative]]
[[:Category:Osteoporosis_medications|Osteoporosis medication]]
[[:Category:Overactive_bladder_medications|Overactive bladder medication]]
[[:Category:P2Y12_inhibitors|P2Y12 receptor inhibitor (reversible)]]
[[:Category:P2Y12_inhibitors|P2Y12 receptor inhibitor]]
[[:Category:PCSK9_inhibitors|PCSK9 inhibitor]]
[[:Category:PPAR_alpha_agonists|PPAR-α agonist]]
[[:Category:PPAR_gamma_agonists|PPAR-γ agonist]]
[[:Category:Penicillins|Penicillin (natural
[[:Category:Penicillins|Penicillin]]
[[:Category:Phenothiazines|Phenothiazine]]
[[:Category:Polyene_antifungals|Polyene antifungal]]
[[:Category:Potassium-sparing_diuretics|Potassium-sparing diuretic]]
[[:Category:Potassium_supplements|Potassium supplement]]
[[:Category:Progestins|Progestin (synthetic progestogen)]]
[[:Category:Progestogens|Progestin (synthetic progestogen)]]
[[:Category:Progestogens|Progestogen]]
[[:Category:Prokinetics|Prokinetic (off-label)]]
[[:Category:Prokinetics|Prokinetic]]
[[:Category:Prostaglandin_analogs|Prostaglandin F2α analog]]
[[:Category:Proton_pump_inhibitors|Proton pump inhibitor (PPI)]]
[[:Category:Psychedelics|Psychedelic]]
[[:Category:Psychostimulants|Psychostimulant]]
[[:Category:Psychostimulants|Psychostimulant]] (atypical)
[[:Category:Pyranocarboxylic_acid_derivatives|Pyranocarboxylic acid derivative]]
[[:Category:REMS medicines|REMS medicine (mandatory ANC monitoring)]]
[[:Category:Rapid-acting_insulins|Rapid-acting insulin analog]]
[[:Category:Retinoids|Retinoid]]
[[:Category:SARIs|Serotonin antagonist and reuptake inhibitor (SARI)]]
[[:Category:SGLT2_inhibitors|SGLT2 inhibitor]]
[[:Category:SNRIs|Serotonin-norepinephrine reuptake inhibitor (SNRI)]]
[[:Category:SSRIs|Selective serotonin reuptake inhibitor (SSRI)]]
[[:Category:SV2A ligands|Synaptic vesicle protein 2A (SV2A) ligand]]
[[:Category:Schedule II controlled substances|Schedule II controlled substance]]
[[:Category:Schedule III controlled substances|Schedule III controlled substance]]
[[:Category:Schedule IV controlled substances|Schedule IV controlled substance]]
[[:Category:Schedule V controlled substances|Schedule V controlled substance]]
[[:Category:Schedule_III_controlled_substances|Schedule III controlled substance]]
[[:Category:Schedule_II_controlled_substances|Schedule II controlled substance]]
[[:Category:Schedule_IV_controlled_substances|Schedule IV controlled substance]]
[[:Category:Second-generation neuroleptics|Second-generation (atypical) neuroleptic]]
[[:Category:Second-generation neuroleptics|Second-generation neuroleptic (atypical)]]
[[:Category:Selective Serotonin Reuptake Inhibitors (SSRIs)|SSRI]]
[[:Category:Serotonin 5-HT1A partial agonists|Serotonin 5-HT1A partial agonist]]
[[:Category:Serotonin antagonists|Serotonin 5-HT2 antagonist]]
[[:Category:Serotonin-dopamine antagonists|Serotonin-dopamine antagonist]]
[[:Category:Sex_hormones|Sex hormone]]
[[:Category:Short-acting_muscarinic_antagonists|Short-acting muscarinic antagonist (SAMA)]]
[[:Category:Sigma-1_receptor_agonists|Sigma-1 receptor agonist]]
[[:Category:Skeletal muscle relaxants|Skeletal muscle relaxant (centrally-acting)]]
[[:Category:Skeletal muscle relaxants|Skeletal muscle relaxant]]
[[:Category:Skin_lightening_agents|Skin-lightening agent]]
[[:Category:Sleep aids|Sleep aid (Silenor low-dose)]]
[[:Category:Sleep aids|Sleep aid (off-label)]]
[[:Category:Sleep aids|Sleep aid]]
[[:Category:Smoking cessation medicines|Smoking cessation medicine]]
[[:Category:Sodium channel blockers|Sodium channel blocker]]
[[:Category:Statins|Statin]]
[[:Category:Stimulant_laxatives|Stimulant laxative]]
[[:Category:Stool_softeners|Stool softener]]
[[:Category:Sulfonylureas|Sulfonylurea (second-generation)]]
[[:Category:Sulfonylureas|Sulfonylurea (third-generation)]]
[[:Category:Surfactants|Surfactant]]
[[:Category:Sympathomimetics|Sympathomimetic (indirect-acting)]]
[[:Category:Sympathomimetics|Sympathomimetic]]
[[:Category:TNF_inhibitors|TNF-α inhibitor]]
[[:Category:Tetracyclic antidepressants|Tetracyclic antidepressant]]
[[:Category:Tetracycline_antibiotics|Tetracycline antibiotic]]
[[:Category:Thiazide-like_diuretics|Thiazide-like diuretic]]
[[:Category:Thiazide_diuretics|Thiazide diuretic]]
[[:Category:Thiazolidinediones|Thiazolidinedione (TZD)]]
[[:Category:Thienobenzodiazepines|Thienobenzodiazepine]]
[[:Category:Thienopyridines|Thienopyridine]]
[[:Category:Thionamides|Thionamide]]
[[:Category:Third-generation neuroleptics|Third-generation neuroleptic]]
[[:Category:Thyroid_hormones|Thyroid hormone]]
[[:Category:Tocolytics|Tocolytic (off-label)]]
[[:Category:Topical_antibiotics|Topical antibiotic]]
[[:Category:Topical_antifungals|Topical antifungal]]
[[:Category:Topical_corticosteroids|Topical corticosteroid (Class I
[[:Category:Topical_corticosteroids|Topical corticosteroid (high-to-super-high potency depending on ester)]]
[[:Category:Topical_corticosteroids|Topical corticosteroid]]
[[:Category:Topical_retinoids|Topical retinoid]]
[[:Category:Trace_elements|Trace element]]
[[:Category:Treatment-resistant schizophrenia medicines|Treatment-resistant schizophrenia medicine]]
[[:Category:Tremor medicines|Tremor medicine]]
[[:Category:Triazoles|Triazole]]
[[:Category:Tricyclic antidepressants|Tricyclic antidepressant (TCA
[[:Category:Tricyclic antidepressants|Tricyclic antidepressant (TCA)]]
[[:Category:Tricyclic-related compounds|Tricyclic-related compound]]
[[:Category:Triptans|Triptan (5-HT1B/1D agonist)]]
[[:Category:Tryptamines|Tryptamine]]
[[:Category:Ultra-long-acting_insulins|Ultra-long-acting insulin analog]]
[[:Category:Urinary_analgesics|Urinary tract analgesic]]
[[:Category:Urinary_anti-infectives|Urinary anti-infective]]
[[:Category:Vasodilators|Vasodilator]]
[[:Category:Vasopressors|Vasopressor]]
[[:Category:Vitamin_D_analogs|Vitamin D analog (active form)]]
[[:Category:Vitamin_D_analogs|Vitamin D analog]]
[[:Category:Vitamin_K_antagonists|Vitamin K antagonist]]
[[:Category:Vitamins|Vitamin]]
[[:Category:Water-soluble_vitamins|Water-soluble vitamin]]
[[:Category:Weight loss medicines|Weight loss medicine]]
[[:Category:Xanthine_oxidase_inhibitors|Xanthine oxidase inhibitor]]
[[GLP-1 receptor agonist]] · [[Antidiabetic medicines|Antidiabetic]] · Fc-fusion biologic
[[GLP-1 receptor agonist]] · [[Antidiabetic medicines|Antidiabetic]] · First-in-class incretin mimetic
[[GLP-1 receptor agonist]] · [[Antidiabetic medicines|Antidiabetic]] · [[Anti-obesity medicines|Anti-obesity]] · [[Cardiovascular risk reduction]] agent
[[GLP-1 receptor agonist]] · [[GIP receptor agonist]] · [[Antidiabetic medicines|Antidiabetic]] · [[Anti-obesity medicines|Anti-obesity]] · "Twincretin"
_none
atypical)]]
gut-restricted)]]
high-potency)]]
hydroxide)]]
kappa antagonist)]]
low-affinity)]]
low-trapping)
narrow-spectrum)]]
neuromuscular blocker (presynaptic)
non-selective)]]
non-stimulant ADHD agent
phytocannabinoid
potent non-selective)]]
precursor cannabinoid
preferential COX-2)]]
secondary amine)]]
selective COX-2)]]
super-potent)]]
targets protofibrils
targets pyroglutamated Aβ in plaques
the first approved
torsades)]]
wake-promoting agent
weak μ-agonist with serotonin/norepinephrine reuptake inhibition)]]
weak)]]
with alpha-1 antagonism)]]
with mineralocorticoid activity)]]
Search
mechanism:
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uses:
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starting dose:
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preparations:
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None
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10 mg, 20 mg, 40 mg, 80 mg tablets
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2.5, 5, 10, 20 mg tabs
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5 mg, 10 mg tablets
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5, 10 mg tablets
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5, 10, 20, 40 mg tablets
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0.005% ophthalmic solution (50 mcg/mL); typical 2.5 mL bottle
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0.01%, 0.03% ophthalmic solution
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0.025%, 0.035% ophthalmic solutions
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0.1% (Patanol), 0.2% (Pataday once-daily original), 0.7% (Pataday 24-hour) ophthalmic solutions; 0.6% nasal spray
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0.1%, 0.15% intranasal spray; 0.05% ophthalmic solution; combination Dymista (azelastine 0.137 mg + fluticasone 50 mcg/spray)
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0.1%, 0.15%, 0.2% ophthalmic solutions; 0.33% topical gel; combinations with timolol (Combigan) and brinzolamide (Simbrinza)
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0.225%, 0.45%, 0.9%, 3%, 5% IV solutions; 0.9% nasal spray; 3% and 7% nebulizer solutions; oral tablets (1 g)
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0.25 mg, 0.5 mg, 1 mg, 2 mg tablets (immediate-release and orally disintegrating); 0.5 mg, 1 mg, 2 mg, 3 mg extended-release tablets; 1 mg/mL oral concentrate
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0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, 4 mg tablets
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0.25, 0.5 mcg oral capsules; 1 mcg/mL oral solution; 1 mcg/mL IV; 3 mcg/g topical ointment
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0.35 mg POP tablets; 5 mg tablets (Aygestin); component of COCs and combination HRT
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0.4 mg capsules
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0.4, 0.8, 1 mg OTC; 1 mg Rx; 5 mg/mL injection
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0.5 g, 1 g capsules
Other values:
0.5 g/mL oral solution
0.5 mg capsules
0.5% (Carac), 1% (Fluoroplex), 5% (Efudex) topical creams/solutions; 50 mg/mL IV
0.5, 0.75, 1, 1.5, 2, 4, 6 mg tablets; oral solution; 4, 10, 20, 100 mg/mL IV; intravitreal implant (Ozurdex)
0.5, 1, 2 mg tablets; 0.25 mg/mL IV
0.6 mg tablets; 0.6 mg/5 mL solution; 0.5 mg tablets (Lodoco)
0.6 mg/5 mL oral solution; Celestone Soluspan 6 mg/mL IM/IA (mix of sodium phosphate + acetate); 0.05% and 0.1% topical cream/ointment/lotion/foam (various salts); augmented betamethasone 0.05% (super-high potency)
0.77% topical cream, lotion, suspension; 1% shampoo; 8% nail lacquer (Penlac)
1 g soft gelatin capsules containing ~465 mg EPA + ~375 mg DHA as ethyl esters
1 g tablets; 1 g/10 mL suspension
1 mg tablets
1 mg, 2 mg, 4 mg tablets
1 mg, 5 mg tablets
1% (OTC), 2% (Rx) shampoo; 2% cream; 2% gel; 200 mg oral tablet (rarely used now)
1% topical cream, lotion, solution; 1%, 2% vaginal cream; 100, 200, 500 mg vaginal tablets; 10 mg oral troches; combination with betamethasone (Lotrisone, Rx)
1, 2, 2.5, 3, 4, 5, 6, 7.5, 10 mg tablets (color-coded by strength)
1, 2, 4, 8 mg IR tablets; 4, 8 mg XL tablets
1, 2, 5 mg caps
1, 2, 5, 10 mg capsules and tablets
1, 2.5, 5, 10, 20, 50 mg tablets; 5 mg/5 mL syrup; 5 mg/mL concentrate
1.25, 2.5, 5, 10 mg capsules
1.5 mg, 3 mg, 4.5 mg, 6 mg capsules
10 g/15 mL solution (Constulose); 10 g, 20 g powder packets (Kristalose)
10 mg tablet; also as fixed-dose combinations with simvastatin (Vytorin) and atorvastatin (Liptruzet, withdrawn US 2015 but generics exist)
10 mg tablets; 4 mg, 5 mg chewables; 4 mg granules
10 mg tablets; 5 mg ODT and chewables; 1 mg/mL oral syrup; combo Claritin-D (with pseudoephedrine, behind-counter)
10 mg, 20 mg, 40 mg caps
10 mg, 20 mg, 40 mg tablets
10 mg, 20 mg, 40 mg tablets; chewables; 40 mg/5 mL oral suspension; 10 mg/mL IV
10 mg, 25 mg tablets
10 mg, 34 mg capsules/tablets
10 mg/spray nasal solution
10, 20 mg IR capsules; 30, 60, 90 mg ER tablets
10, 20 mg tablets/capsules; 10 mg/5 mL syrup; 10 mg/mL IM injection
10, 20, 40 mg delayed-release capsules and tablets; 2 mg/mL oral suspension; immediate-release combo with sodium bicarbonate (Zegerid)
10, 20, 40 mg tablets; 20, 40, 60 mg ER tablets
10, 20, 40, 60, 80 mg tabs; 60/80/120/160 mg ER caps; 1 mg/mL IV
10, 25, 50, 100 mg tablets; 20 mg/mL IV
100 U/mL (FlexTouch pen) and 200 U/mL (FlexTouch pen, higher-dose convenience)
100 U/mL (Humalog, Admelog, Lyumjev) vials, pens, cartridges; 200 U/mL Humalog KwikPen
100 U/mL (Lantus, Basaglar, Semglee) vials and pens; 300 U/mL (Toujeo) pens
100 U/mL (NovoLog, Fiasp) vials, pens, cartridges
100 U/mL FlexTouch pen, vial
100 mg tabs
100 mg, 150 mg, 200 mg extended-release capsules (can be sprinkled on food)
100 mg, 300 mg tablets; IV 500 mg vial
100 mg/20 mL vial, single-use
100 mg/mL vial for IV infusion
100, 150, 200 mg liquid-filled capsules ("perles")
100, 200, 400 IU softgels and capsules; many proprietary OTC blends; combined formulations (AREDS-2)
100, 200, 400 mg IR tablets; 600 mg, 1200 mg Mucinex ER tablets; many liquid formulations and combination products with dextromethorphan, pseudoephedrine, antihistamines
100, 200, 400 mg tablets; 50 mg/mL IV (with polysorbate 80 in older formulations causing hypotension); 1.5 mg/mL Nexterone IV (PVC-free, lower hypotension risk)
100, 250, 500, 1000 mg tablets, chewables, gummies, effervescent; IV (specialty)
100, 250, 500, 1000, 5000 mcg tablets (OTC and Rx); 1000 mcg/mL injection; intranasal spray; sublingual
100,000 units/mL oral suspension; 500,000 unit tablets; 100,000 units/g cream, ointment, powder; vaginal tablets
12.5 mg capsules; 12.5, 25, 50 mg tablets
120 mg/mL prefilled syringe or autoinjector
125, 250, 500 mg delayed-release tablets (Depakote); 250, 500 mg ER tablets (Depakote ER); 125, 250 mg sprinkle capsules; 250 mg/5 mL syrup; 500 mg IV (Depacon)
125, 250, 500 mg tablets; 125 mg/5 mL, 250 mg/5 mL suspension; 750 mg, 1.5 g IV vials
140 mg/mL single-use prefilled syringe and SureClick autoinjector; Pushtronex 420 mg/3.5 mL on-body infusor
15 mg, 25 mg, 50 mg tablets
15, 30, 37.5 mg capsules/tablets; 8 mg Lomaira
15, 30, 45 mg tablets
15, 30, 60, 90, 120, 180, 240, 300 mg tablets (1/4 to 5 grains; 1 grain = 60 mg)
17 g (OTC) and 14 g (Rx) powder packets; 238, 510, 527 g bottles; PEG-electrolyte preparations 4 L (GoLYTELY, NuLYTELY)
18 mcg HandiHaler capsules; 2.5 mcg/actuation Respimat solution inhaler (1.25 mcg/actuation for asthma indication)
2 mg capsules and tablets; 1 mg/5 mL oral solution; combined with simethicone (Imodium Multi-Symptom)
2% ointment; 2% cream; 2% nasal ointment (Bactroban Nasal)
2% ophthalmic solution (Trusopt); 2%/0.5% fixed combination with timolol (Cosopt, Cosopt PF)
2%, 4% wash; 2% CHG/70% IPA applicators (ChloraPrep); 0.12%, 0.2% oral rinse; impregnated catheter dressings
2, 4, 8, 16, 32 mg oral tablets; 40, 125, 500, 1000 mg IV vials; Depo-Medrol 20, 40, 80 mg/mL IM depot
2.5 mg tablets; 10-50 mg/mL injection; pre-filled subcutaneous autoinjectors (Otrexup, Rasuvo); 2.5 mg/mL oral solution (Xatmep)
2.5 mg, 5 mg tablets
2.5, 10, 15, 20 mg tablets
2.5, 5, 10 mg oral tablets; Depo-Provera 150 mg/mL IM; Depo-SubQ Provera 104 mg/0.65 mL
2.5, 5, 10 mg tablets; 1 mg/mL oral suspension
2.5, 5, 10, 20 mg tablets; 1 mg/mL oral solution (Epaned); 1.25 mg/mL IV (enalaprilat)
2.5, 5, 10, 20 mg tabs (Levitra); 10 mg ODT (Staxyn)
2.5, 5, 10, 20, 30, 40 mg tablets; 1 mg/mL oral solution
20 mg dextromethorphan HBr / 10 mg quinidine sulfate capsules
20 mg, 25 mg, 30 mg capsules
20 mg, 40 mg delayed-release tablets; 40 mg IV vial; oral suspension 40 mg/packet
20, 40 mg delayed-release capsules; 2.5, 5, 10, 20, 40 mg oral suspension packets; 20, 40 mg IV
20, 40, 80 mg tablets
20, 40, 80 mg tablets; 10 mg/mL oral solution; 10 mg/mL IV
200 mg tablets; 100 mg/5 mL suspension
200 mg/2 mL, 500 mg/5 mL vials for IV infusion
200, 300, 400 mg tablets (mostly generic now); 0.3% ophthalmic solution; 0.3% otic solution
200, 300, 400, 500 mg IR tablets/capsules; 400, 500, 600 mg ER tablets
200, 400, 800 mg tablets; 200 mg capsules; 200 mg/5 mL suspension; 500, 1000 mg IV vials; 5% cream and ointment (topical)
225 mg/1.5 mL prefilled syringe or autoinjector
25 mg, 50 mg tablets
25 mg, 50 mg, 100 mg tablets
25 mg, 50 mg, 100 mg tablets; 25 mg/5 mL oral suspension (CaroSpir)
25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL
25 mg, 50 mg, 100 mg, 200 mg, 300 mg, 400 mg immediate-release tablets; 50 mg, 150 mg, 200 mg, 300 mg, 400 mg extended-release tablets (Seroquel XR)
25 mg/5 mL suspension; 25, 50, 100 mg capsules (Macrodantin); 100 mg Macrobid capsule
25, 50 mg ER tablets; 8 mg/mL granules for oral suspension (Myrbetriq Granules, pediatric)
25, 50, 100 mg tablets; combination tablets with metformin
25, 50, 100 mg tabs (Viagra); 20 mg tabs and 10 mg/mL oral suspension (Revatio)
25, 50, 100, 250, 400 mg tablets; OTC
25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200, 300 mcg tablets; oral capsule and IV/IM also available
250 mg tablets; 1% topical cream, gel, spray; granules (pediatric)
250 mg, 500 mg capsules; 500 mg, 875 mg tablets; 125, 200, 250, 400 mg/5 mL oral suspension; 775 mg ER; 50 mg/mL drops
250 mg, 500 mg tablets; 125 mg/5 mL, 250 mg/5 mL suspension
250 mg, 500 mg, 600 mg tablets; 100, 200 mg/5 mL suspension; 2 g ER suspension (Zmax); 500 mg IV
250 mg, 500 mg, 750 mg capsules; 250 mg/5 mL, 125 mg/5 mL suspension; tablets
250, 500 mg base or stearate tablets; ER tablets; ethyl succinate 200 mg/5 mL suspension; 500 mg, 1 g IV (lactobionate); 2% topical solution/gel; 0.5% ophthalmic ointment
250, 500 mg tablets; 750 mg ER; 500 mg/100 mL IV; 0.75-1% topical gel/cream; 0.75% vaginal gel; suppository
250, 500, 1000 mL IV bags. Composition per liter: Na+ 130 mEq, K+ 4 mEq, Ca2+ 3 mEq, Cl- 109 mEq, lactate 28 mEq
250, 500, 750 mg IR tablets; 500, 1000 mg ER tablets (XR); 250, 500 mg/5 mL oral suspension; 200, 400 mg IV; 0.3% ophthalmic solution and ointment; 0.2% otic
250, 500, 750 mg tablets; 25 mg/mL oral solution; 25 mg/mL IV (premix bags 250, 500, 750 mg); 0.5%, 1.5% ophthalmic solutions
28 mg/device (each dose uses 2 devices)
3 mg tablets (Stromectol); 0.5% topical lotion (Sklice); 1% topical cream (Soolantra)
30, 45, 75 mg capsules; 6 mg/mL oral suspension
30, 60, 180 mg tablets; 30 mg ODT; 6 mg/mL oral suspension; all OTC
300 mg capsules; 125, 250 mg/5 mL suspension
325 mg tablets (65 mg elemental Fe); 220 mg/5 mL liquid (44 mg elemental Fe/5 mL); 142 mg/mL drops; OTC and Rx
325, 500, 650 mg tablets; 80, 160 mg chewables; 160 mg/5 mL pediatric liquid; 325 mg suppository; 1000 mg/100 mL IV (Ofirmev); fixed-dose combinations with opioids, decongestants, antihistamines
350 mg/20 mL vial for IV infusion
4 mg, 8 mg, 24 mg tablets; 4 mg, 8 mg orally disintegrating tablets; 4 mg/5 mL oral solution; IV (2 mg/mL)
4% prescription cream/lotion; OTC 2% withdrawn in US (2020 CARES Act); compounded higher strengths available
4.2%, 7.5%, 8.4% IV (1 mEq/mL at 8.4%); 325, 650 mg oral tablets; bulk powder
4.45 mg, 17.8 mg tablets
4.8355 mg oxycodone / 325 mg aspirin tablets
40 mg/0.4 mL or 40 mg/0.8 mL prefilled syringe and autoinjector pen; 10, 20, 80 mg pediatric/induction strengths
40, 80, 160, 320 mg tablets; oral suspension
400 mg tablets; 400 mg/250 mL IV; 0.5% ophthalmic solution
42 mg capsules
5 mg IR tablets; 5, 10, 15 mg ER tablets; 5 mg/5 mL syrup; 3.9 mg/24 h transdermal patch (Oxytrol); 10% topical gel
5 mg enteric-coated tablets; 10 mg rectal suppositories; OTC and Rx
5 mg tablets; 2.5 mg/5 mL oral solution; OTC
5 mg tablets; 5 mg/5 mL, 10 mg/5 mL, 15 mg/5 mL oral solutions (sweetened pediatric); 5 mg/5 mL syrup; ophthalmic 0.12%, 1% suspensions and 1% solution
5 mg tablets; combination with metformin
5 mg, 10 mg immediate-release tablets; 2.5 mg, 5 mg, 10 mg extended-release tablets
5 mg, 10 mg tablets; 5 mg, 10 mg chewables; 1 mg/mL oral syrup; OTC
5 mg, 10 mg, 15 mg, 20 mg tablets
5 mg, 10 mg, 20 mg tablets
5, 10 mg tablets; 5 mg/5 mL solution; 5 mg/mL IV; 15 mg/spray intranasal
5, 10 mg tabs
5, 10, 20 mg oral tablets; 100, 250, 500, 1000 mg IV (Solu-Cortef); 0.5%, 1%, 2.5% topical creams/ointments; rectal foam and enemas
5, 10, 20, 100 mg tablets; 10 mg/mL IV
5, 10, 20, 40, 80 mg tablets; 4 mg/mL oral suspension
5, 10, 35, 40, 70 mg tablets; 70 mg/75 mL oral solution; 70 mg effervescent (Binosto)
5, 20, 40 mg tablets
5, 25, 50 mcg tablets (Cytomel); 10 mcg/mL IV (Triostat)
50 mg, 75 mg, 100 mg, 150 mg tablets and capsules; delayed-release; suspension; IV
50, 100, 150 mg tablets
50, 100, 150, 200 mg tablets; 10, 40 mg/mL oral suspension; 2 mg/mL IV
50, 100, 200 mg tabs
50, 100, 250 mg capsules; 50 mg/5 mL syrup; OTC
50, 100, or 200 unit vials of lyophilized powder for reconstitution
50,000 IU capsules (Rx); 8,000 IU/mL oral solution (Rx); 400-5,000 IU OTC tablets and softgels
50/325/40 mg capsules
50/325/40 mg capsules and tablets; oral solution
500 mg, 1 g tablets
500 mg, 850 mg, 1000 mg IR tablets; 500 mg, 750 mg, 1000 mg ER tablets; 500 mg/5 mL oral solution
500, 750 mg tablets
60, 90 mg tablets
7/10, 14/10, 21/10, 28/10 mg ER capsules (memantine ER / donepezil)
70 mg/mL or 140 mg/mL prefilled autoinjector
72, 145, 290 mcg capsules
75 mg, 150 mg tablets
75 mg, 300 mg tablets
75, 150, 300 mg capsules; 75 mg/5 mL solution; 150 mg/mL IV; 1% topical; 2% vaginal cream
75, 150, 300 mg tablets
8 mg naltrexone / 90 mg bupropion ER tablets (titration-pack design)
8, 10, 20, 25 mEq tablets/capsules (most ER); effervescent and oral solution; IV concentrate (must be diluted)
85 mg sumatriptan / 500 mg naproxen sodium tablets; lower-dose 10/60 mg pediatric (Treximet pediatric)
95 mg (OTC), 99.5 mg, 100 mg, 200 mg tablets
A ''betel quid'': areca nut slice + betel leaf + slaked lime (calcium hydroxide) ± tobacco ± spices, chewed
Acid/base extraction of fresh young grass for tryptamines; combined with an MAOI
Atrovent HFA 17 mcg/actuation MDI; 500 mcg/2.5 mL nebulizer solution; 0.03% and 0.06% intranasal sprays; with albuterol as DuoNeb / Combivent Respimat
Auto-injectors 0.15 mg (Jr/pediatric), 0.3 mg (adult); 1 mg/mL (1:1,000) ampules for IM/SC use; 0.1 mg/mL (1:10,000) for IV use; 2.25% racemic nebulizer
Bark/woody stem decocted with a DMT-source plant (''Psychotria viridis'', ''Diplopterys cabrerana'') to make ayahuasca
Bicillin L-A 600,000; 1.2M; 2.4M U IM; aqueous crystalline (Pfizerpen) 5M, 20M U IV; procaine 600,000 U/mL IM
Bright red seeds, traditionally ingested or smoked. Highly toxic, narrow margin between active and lethal
Byetta pre-filled multi-dose pen: 5 µg / 10 µg per dose'"`UNIQ--ref-000000E5-QINU`"' · Bydureon BCise single-dose autoinjector: 2 mg extended-release microsphere suspension'"`UNIQ--ref-000000E6-QINU`"'
Capsules 10, 18, 25, 40, 60, 80, 100 mg
Capsules 10, 20, 30, 40, 50, 60, 70 mg; chewable tablets 10, 20, 30, 40, 50, 60 mg
Capsules 10, 25, 50, 75 mg; oral solution 10 mg/5 mL
Capsules 10, 25, 50, 75, 100, 150 mg; oral concentrate 10 mg/mL; Silenor tablets 3, 6 mg; topical cream 5% (Prudoxin, Zonalon)
Capsules 100, 300, 400 mg; tablets 600, 800 mg; oral solution 250 mg/5 mL; Gralise ER tablets 300, 600 mg (once-daily); Horizant ER tablets 300, 600 mg (gabapentin enacarbil, an inactive parent compound metabolized to gabapentin in vivo)
Capsules 25, 50 mg; ER capsules 75 mg; oral suspension 25 mg/5 mL; suppositories 50 mg; injection 1 mg/vial (PDA closure)
Capsules 25, 50, 75, 100, 150, 200, 225, 300 mg; oral solution 20 mg/mL; Lyrica CR tablets 82.5, 165, 330 mg
Capsules 50, 100, 200, 400 mg; Elyxyb oral solution 25 mg/mL
Capsules: 3/25, 6/25, 6/50, 12/25, 12/50 mg olanzapine/fluoxetine
Carbonate 200, 400, 500, 600 mg elemental tablets and chewables; citrate 200, 250, 315 mg elemental; gluconate 1 g (94 mg elemental, 4.65 mEq) IV; chloride 1 g (270 mg elemental, 13.6 mEq) IV
Clozaril 25 mg and 100 mg tablets; FazaClo orally disintegrating tablets (12.5/25/100/150/200 mg); Versacloz oral suspension 50 mg/mL. All brands subject to identical REMS ANC monitoring requirements. Generic tablets widely available.
Codeine/acetaminophen 15/300 (#2 historical), 30/300 (#3), 60/300 (#4) mg tablets; 12/120 mg/5 mL elixir
Cream, ointment, lotion, foam, solution, shampoo, spray at 0.025-0.05%; emollient and non-emollient bases
Desoxyn 5 mg tabs
Dextromethorphan 45 mg + bupropion 105 mg ER tablets
Dried leaves and twigs, infused in a gourd (''mate'') and drunk through a metal straw (''bombilla'')
Dried leaves, infused. Six major processings: white, green, yellow, oolong, black, pu-erh
Dried leaves; absinthe liqueur (120–160 proof, with hyssop, lemon balm, fennel, anise, sometimes Acorus calamus)
ER tablets 25, 50, 100 mg
Extended-release tablets 1, 2, 3, 4 mg (Intuniv); immediate-release tablets 1, 2 mg (Tenex)
Fermented and roasted seeds, ground. Mexican tradition: drunk with chili, cornmeal, achiote. European tradition: with sugar and milk
Flowers or leaves infused or smoked. Highly variable potency; narrow toxic margin
Fresh leaves and tender twigs chewed; degrades on drying
Fresh nuts chewed; also dried and powdered
Gels, patches, IM cypionate/enanthate/undecanoate, buccal tabs, nasal gel, oral undecanoate, subcutaneous pellets
Ground dried seed (nutmeg) or fruit aril (mace); occasionally infused
Historical: Sernyl 25 mg tablets, 10 mg/mL injection (human); Sernylan 100 mg/mL injection (veterinary). Illicit: white crystalline powder, oily liquid, "dipped" cigarettes ("wet"), tablets.
IR 30, 60, 90, 120 mg tablets; multiple ER capsules and tablets 60-420 mg; IV 5 mg/mL
IR 40, 80, 120 mg tablets; SR/ER 100-360 mg; IV 2.5 mg/mL
IR tablets 0.1, 0.2, 0.3 mg; ER tablets 0.1, 0.2 mg (Kapvay); transdermal patches 0.1, 0.2, 0.3 mg/24h (TTS-1/2/3, weekly); epidural injection (Duraclon)
IR tablets 0.125, 0.25, 0.5, 0.75, 1, 1.5 mg; ER tablets 0.375, 0.75, 1.5, 2.25, 3, 3.75, 4.5 mg
IR tablets 0.25, 0.5, 1, 2, 3, 4, 5 mg; XL tablets 2, 4, 6, 8, 12 mg
IR tablets 10, 20, 30, 40 mg; CR tablets 12.5, 25, 37.5 mg; oral suspension 10 mg/5 mL; Brisdelle capsules 7.5 mg
IR tablets 15, 30 mg; oral solution 10 mg/5 mL, 20 mg/mL, 100 mg/5 mL (concentrated); suppositories; ER tablets and capsules in multiple strengths; injectable 0.5-50 mg/mL
IR tablets 150, 300, 600 mg; oral suspension 60 mg/mL; XR tablets 150, 300, 600 mg (Oxtellar)
IR tablets 200 mg; chewable 100 mg; oral suspension 100 mg/5 mL; XR tablets 100, 200, 400 mg (Tegretol XR); ER capsules 100, 200, 300 mg (Carbatrol, Equetro)
IR tablets 25, 100, 150, 200 mg; chewable dispersible tablets 2, 5, 25 mg; ODT 25, 50, 100, 200 mg; XR tablets 25, 50, 100, 200, 250, 300 mg
IR tablets 25, 37.5, 50, 75, 100 mg; XR capsules 37.5, 75, 150, 225 mg
IR tablets 25, 50 mg; ER tablets 100 mg; Cataflam IR 50 mg; Zorvolex 18, 35 mg; Voltaren gel 1%; Pennsaid 2% topical solution; Flector transdermal patch; Solaraze 3% gel; Cambia oral powder 50 mg
IR tablets 25, 50, 100 mg; Luvox CR capsules 100, 150 mg
IR tablets 25, 50, 100, 200 mg; sprinkle capsules 15, 25 mg; Trokendi XR capsules 25, 50, 100, 200 mg; Qudexy XR capsules; Eprontia oral solution 25 mg/mL
IR tablets 250, 500, 750, 1000 mg; XR tablets 500, 750 mg; oral solution 100 mg/mL; injection 100 mg/mL; Spritam ODT 250, 500, 750, 1000 mg
IR tablets 3.125, 6.25, 12.5, 25 mg; Coreg CR capsules 10, 20, 40, 80 mg (once-daily)
IR tablets 30, 60 mg; 12-hour ER tablets 120 mg; 24-hour ER tablets 240 mg; oral liquid; multiple combination products with antihistamines, NSAIDs, or expectorants
IR tablets 5, 10 mg; CR tablets 6.25, 12.5 mg; SL tablets 1.75, 3.5, 5, 10 mg; oral spray
IR tablets 5, 10 mg; oral solution 2 mg/mL; XR capsules 7, 14, 21, 28 mg
IR tablets 5, 7.5, 10 mg; Amrix ER capsules 15, 30 mg
IR tablets 5, 7.5, 10, 15, 20, 30 mg; IR oral solution 5 mg/5 mL; concentrated solution 20 mg/mL; OxyContin ER tablets 10, 15, 20, 30, 40, 60, 80 mg; Xtampza ER capsules
IR tablets 50 mg; ER tablets 100, 200, 300 mg (Ultram ER, ConZip); oral solution 5 mg/mL; combination products with acetaminophen (Ultracet)
IR tablets 50, 100, 150, 300 mg; Oleptro ER tablets 150, 300 mg
IR tabs 5, 7.5, 10, 12.5, 15, 20, 30 mg; XR caps 5, 10, 15, 20, 25, 30 mg; Mydayis caps 12.5, 25, 37.5, 50 mg
IV 10 mg/mL, 40 mg/mL; inhaled 300 mg/5 mL solution (Tobi, Bethkis); Podhaler dry powder; 0.3% ophthalmic solution and ointment
Illicit tablets ("bars"), powders, blotter, occasionally solutions. No pharmaceutical product exists.
Inhaled MDI 44/110/220 mcg per actuation; DPI (Diskus) 50/100/250 mcg; nasal spray 50 mcg/actuation; cream/ointment 0.005%, 0.05%
Injection 0.5-4% solutions (with and without epinephrine); topical cream 4-5%; transdermal patch 5% (Lidoderm), 1.8% (ZTLido); oral 2% viscous solution; jelly 2%; ophthalmic
Investigational oral capsule
Leaves and seeds, traditionally smoked or infused. Possibly the original Pythia oracle plant
Leaves chewed with a pinch of slaked lime (the lime converts cocaine HCl to freebase for buccal absorption); also drunk as tea (''mate de coca'')
Leaves, berries, root. Historically: belladonna cigarettes ("Asthmador") OTC in US until the 1970s
Lithium carbonate: immediate-release capsules (150 mg, 300 mg, 600 mg) and tablets (300 mg); extended-release tablets (300 mg, 450 mg). Lithium citrate: oral solution (8 mEq/5 mL, equivalent to 300 mg lithium carbonate per 5 mL) for patients unable to swallow tablets.
MDI 90 mcg/puff; nebulizer solution 0.083% (2.5 mg/3 mL), 0.5%, 0.021%, 0.042%; syrup 2 mg/5 mL; 2 mg, 4 mg tablets; 4 mg, 8 mg ER
Mononitrate 10, 20 mg IR; 30, 60, 120 mg ER; dinitrate 5, 10, 20, 30, 40 mg IR and ER
Multiple non-bioequivalent fenofibrate and fenofibric acid formulations: 48-200 mg
Multiple non-bioequivalent oral formulations (pH-, time-, and moisture-dependent release); rectal enema 4 g/60 mL; 1 g rectal suppository
Nasonex 50 mcg/actuation intranasal; Asmanex HFA MDI 100/200 mcg; Asmanex Twisthaler DPI 110/220 mcg; Elocon 0.1% cream/ointment/lotion; Sinuva sinus implant; Dulera (with formoterol)
OTC 400, 1,000, 2,000, 5,000 IU softgels and tablets; Rx 50,000 IU capsules; liquid drops 400-2,000 IU/drop
OTC IR niacin 50-500 mg tablets; Niaspan ER 500, 750, 1000 mg tablets; "no-flush" niacin (inositol hexaniacinate, lacks evidence)
OTC tablets 220 mg; Rx tablets 250, 375, 500 mg; ER tablets 375, 500, 750 mg (Naprelan); oral suspension 125 mg/5 mL; enteric-coated tablets (EC-Naprosyn)
OTC tablets, sublingual tablets, gummies, liquid, extended-release tablets and capsules; common strengths 0.5, 1, 3, 5, 10 mg
Oral 0.5, 1, 2 mg tablets; transdermal patches (twice-weekly and once-weekly); 0.06% gel; 1.53 mg/spray topical; vaginal ring (Estring); vaginal tablet (Vagifem/Yuvafem); vaginal cream
Oral 100, 200 mg capsules (peanut oil; check allergy); 100 mg vaginal insert (Endometrin); 4%, 8% vaginal gel (Crinone); IM 50 mg/mL
Oral tablets 25, 50, 100 mg; SC injection 4, 6 mg autoinjector; needle-free SC 6 mg (Sumavel); nasal spray 5, 20 mg; nasal powder 22 mg (Onzetra Xsail); low-dose autoinjector 3 mg (Zembrace SymTouch)
Oral tablets 5, 10, 23 mg; ODT 5, 10 mg; Adlarity transdermal patch 5, 10 mg/day (weekly application)
Oral tablets 50 mg (ReVia, Depade, generics); Vivitrol extended-release IM suspension 380 mg single-dose vial; Contrave (naltrexone 8 mg + bupropion 90 mg ER tablets); compounded 1, 2, 3, 4.5 mg tablets/capsules for LDN
Orally disintegrating tablet 75 mg
Oxide 400, 500 mg tablets (240, 300 mg elemental); citrate 100, 150, 200 mg tablets; hydroxide oral suspension 400 mg/5 mL; sulfate IV 500 mg/mL ampules
Oxycodone/acetaminophen 2.5/325, 5/325, 7.5/325, 10/325 mg tablets; 5/325 mg/5 mL solution
Parotid-gland venom expressed onto a glass plate, dried into a shellac-like resin, vaporized and inhaled
Powder for oral solution in 4 L jugs (PEG 3350 ~236 g + NaCl, NaHCO3, KCl, Na2SO4) and low-volume packets
Pre-filled multi-dose pen (0.25 / 0.5 / 1 / 2 mg, Ozempic;'"`UNIQ--ref-00000248-QINU`"' 0.25 / 0.5 / 1 / 1.7 / 2.4 mg, Wegovy'"`UNIQ--ref-00000249-QINU`"') · Oral tablet 3 / 7 / 14 mg co-formulated with SNAC absorption enhancer (Rybelsus)'"`UNIQ--ref-0000024A-QINU`"'
Pre-filled multi-dose pen (3 mL): Victoza 6 mg/mL (0.6 / 1.2 / 1.8 mg per day);'"`UNIQ--ref-00000183-QINU`"' Saxenda 6 mg/mL (0.6 / 1.2 / 1.8 / 2.4 / 3.0 mg per day)'"`UNIQ--ref-00000184-QINU`"'
Pre-filled single-dose pen and vial: 2.5 / 5 / 7.5 / 10 / 12.5 / 15 mg'"`UNIQ--ref-000002FC-QINU`"''"`UNIQ--ref-000002FD-QINU`"'
Pre-filled single-dose pen: 0.75 / 1.5 / 3 / 4.5 mg'"`UNIQ--ref-00000054-QINU`"'
Pulmicort Flexhaler DPI 90, 180 mcg/dose; Pulmicort Respules 0.25, 0.5, 1 mg/2 mL nebulized; Rhinocort intranasal 32 mcg/spray; Entocort EC 3 mg capsules; Uceris 9 mg ER tablets and rectal foam
Roasted beans, ground; brewed (drip, French press, espresso, cold brew, percolated)
Roasted seeds ground to powder, mixed with water; commercial syrups and energy drinks
Root bark acid/base-extracted for DMT; or as the resurrected ''jurema preta'' brew (decocted with an MAOI such as ''Peganum harmala'')
Root, traditionally carved into ''mannikens'' or infused into wine
SL 0.3, 0.4, 0.6 mg tablets; lingual spray 0.4 mg/spray; ER 2.5-9 mg capsules; transdermal patch 0.1-0.8 mg/hr; 2% ointment; 0.4% rectal ointment; 5 mg/mL IV
SL film or tablet, 2/0.5 to 12/3 mg per dose
SR tablets 100, 150, 200 mg; XL tablets 150, 300 mg; IR tablets 75, 100 mg (less common); Aplenzin (bupropion hydrobromide) 174, 348, 522 mg
Sandimmune 25, 100 mg capsules; Neoral 25, 100 mg modified soft gel; 100 mg/mL oral solution; 50 mg/mL IV; Restasis 0.05% ophthalmic emulsion
Synthesized psilocybin capsules (COMP360 and other investigational formulations); dried whole [[Psilocybe|Psilocybe]] mushrooms (variable potency, no legal supply chain in most jurisdictions); psilocybin truffles (Psilocybe sclerotia, legal in the Netherlands)
Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen).
Tablets 0.25, 0.5, 1, 2, 3, 4 mg; M-Tab ODT 0.5, 1, 2, 3, 4 mg; oral solution 1 mg/mL; Consta LAI 12.5, 25, 37.5, 50 mg; Perseris SC LAI 90, 120 mg monthly
Tablets 0.5, 1, 2 mg; oral concentrate 2 mg/mL; injection 2 mg/mL and 4 mg/mL; Loreev XR capsules 1, 2, 3 mg
Tablets 0.5, 1, 2 mg; orally disintegrating tablets 0.125, 0.25, 0.5, 1, 2 mg
Tablets 10 mg; injection 15 mg/mL and 30 mg/mL; nasal spray 15.75 mg/spray (Sprix); ophthalmic solution 0.4%, 0.45%, 0.5%
Tablets 10, 20, 40 mg; oral solution 10 mg/5 mL
Tablets 10, 25, 50 mg (HCl); capsules 25, 50, 100 mg (pamoate); oral suspension 25 mg/5 mL; injection 25, 50 mg/mL (IM only, never IV)
Tablets 10, 25, 50, 75, 100, 150 mg
Tablets 100, 200, 300 mg; injection 5 mg/mL
Tablets 12.5, 25 mg; chewable tablets 25 mg
Tablets 12.5, 25, 50 mg; oral syrup 6.25 mg/5 mL; suppositories 12.5, 25, 50 mg; injection 25 mg/mL and 50 mg/mL
Tablets 2, 4 mg; capsules 2, 4, 6 mg ('''capsules and tablets are not bioequivalent''': capsules slower with food; tablets faster on empty stomach)
Tablets 2, 5, 10 mg; oral solution 1, 5 mg/mL; injection 5 mg/mL; Diastat rectal gel 2.5, 5, 10, 20 mg; Valtoco nasal spray 5, 7.5, 10 mg/dose; Libervant buccal film
Tablets 2, 5, 10, 15, 20, 30 mg; ODT 10, 15 mg; oral solution 1 mg/mL; acute IM injection 9.75 mg/1.3 mL; Maintena LAI 300, 400 mg monthly; Aristada LAI 441, 662, 882, 1064 mg (4-8 week dosing); Asimtufii bi-monthly
Tablets 2.5, 5, 7.5, 10, 15, 20 mg; ODT (Zydis) 5, 10, 15, 20 mg; acute IM injection 10 mg/vial; Relprevv LAI 210, 300, 405 mg vials
Tablets 200, 400, 600, 800 mg; capsules 200 mg; oral suspension 100 mg/5 mL; chewable tablets 100 mg; injection 100 mg/mL (Caldolor)
Tablets 25, 50 mg; capsules; liquid; chewable; topical cream/gel; injection 50 mg/mL
Tablets 25, 50, 100 mg
Tablets 4 mg; oral syrup 2 mg/5 mL
Tablets 5, 10 mg; ODT (Maxalt-MLT) 5, 10 mg
Tablets 5, 10, 20 mg; ophthalmic solution 0.25%, 0.5%; ophthalmic gel-forming solution 0.25%, 0.5% (Timoptic-XE)
Tablets 5, 10, 20 mg; oral solution 1 mg/mL
Tablets 5, 10, 20 mg; oral suspension 5 mg/5 mL (Ozobax, Fleqsuvy); intrathecal injection 50, 500, 1000, 2000 mcg/mL (Lioresal Intrathecal, Gablofen); oral granules (Lyvispah)
Tablets 5, 10, 40 mg (40 mg dispersible restricted to OTPs); oral concentrate 10 mg/mL; oral solution 1, 2, 10 mg/mL; injection 10 mg/mL
Tablets 5, 7.5, 10, 15, 30 mg (the 15 and 30 mg tablets are scored for halving and quartering)
Tablets 50, 250 mg
Tablets 500, 750 mg; injection 100 mg/mL
Tablets 7.5, 15 mg (Mobic); capsules 5, 10 mg (Vivlodex); oral suspension 7.5 mg/5 mL; injection 30 mg/mL (Anjeso)
Tablets 7.5, 15, 30, 45 mg; orally disintegrating tablets (SolTab) 15, 30, 45 mg
Tablets 81 (low-dose), 325, 500, 650 mg; chewable 81 mg; enteric-coated tablets; effervescent tablets; suppositories
Tablets: 100 mg, 200 mg (scored). [[Armodafinil]] (Nuvigil), the R-enantiomer of modafinil, is available separately as 50 mg, 150 mg, 200 mg, and 250 mg tablets.
Tartrate: 25, 50, 100 mg tabs; 1 mg/mL IV. Succinate ER: 25, 50, 100, 200 mg.
Toasted leaves and twigs decocted to a near-black concentrate
Toothpaste, rinse, gel, varnish (topical); 0.25, 0.5, 1 mg tablets and drops (Rx supplements where appropriate)
Topical 0.01-0.1% creams, gels, micropsheres, lotions; oral 10 mg capsules (Vesanoid)
Topical creams, ointments, lotions, dental paste (0.025-0.5%); Kenalog 10 mg/mL, 40 mg/mL injection; Nasacort 55 mcg/spray intranasal; oral inhaler discontinued in US
Tramadol/acetaminophen 37.5/325 mg tablets
Was: 170 mg/1.7 mL, 300 mg/3 mL vials for IV infusion
Search
fda max:
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routes:
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onset:
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duration:
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halflife:
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bioavailability:
(There are no values for this filter)
pregnancy:
(Click arrow to add another value)
None
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Category C
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Limited data; avoid
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Limited data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
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Limited human data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
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Limited data
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Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-0000002B-QINU`"'
·
Category B
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Chronic third-trimester exposure produces neonatal opioid withdrawal syndrome and respiratory depression at delivery.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Generally considered safe (minimal systemic absorption).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Limited data; switch to insulin where feasible.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Limited data; weigh against alternatives.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
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Previously Category X; FDA removed the blanket statin contraindication in pregnancy in 2021.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
'''Avoid in pregnancy where alternatives exist''' (animal cartilage toxicity; class-wide concern).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Avoid in second and third trimesters; fetal SGLT2 inhibition disrupts kidney development.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
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Avoid where possible; class concerns as for other loop diuretics.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Generally considered safe due to minimal systemic absorption.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Generally considered safe in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Generally considered safe.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
·
Generally considered safe; minimal systemic exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Other values:
'''Among the least preferred SSRIs in pregnancy.''' Observational signal for cardiac malformations (atrial and ventricular septal defects) with first-trimester exposure, and the most severe neonatal adaptation syndrome of any SSRI with third-trimester exposure'"`UNIQ--ref-0000002D-QINU`"'
'''Among the safest antihypertensives in pregnancy''', recommended for chronic hypertension during pregnancy and first-line for severe hypertension in preeclampsia and eclampsia'"`UNIQ--ref-0000001C-QINU`"'
'''Among the safest mood stabilizers in pregnancy''' with reassuring monotherapy registry data, in sharp contrast to valproate. Estrogen-containing contraceptives accelerate lamotrigine metabolism, requiring dose adjustments at start and stop of contraception'"`UNIQ--ref-00000027-QINU`"'
'''Avoid at term (38-42 weeks) and during labor''' (risk of neonatal hemolytic anemia, especially with G6PD deficiency); generally safe in earlier pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
'''Avoid in pregnancy where alternatives exist''' (animal cartilage toxicity).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
'''Avoid in pregnancy where alternatives exist''' (animal cartilage toxicity; class-wide concern); use only when benefit clearly outweighs.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
'''Considered one of the safest anticonvulsants in pregnancy''', with reassuring monotherapy registry data comparable to lamotrigine and in sharp contrast to valproate, topiramate, and carbamazepine'"`UNIQ--ref-00000021-QINU`"'
'''Contraindicated for migraine prophylaxis in pregnancy; high teratogenic risk''' (neural tube defects, craniofacial anomalies, cardiac defects, cognitive/IQ impairment); avoid in women of childbearing potential without reliable contraception when alternatives exist'"`UNIQ--ref-0000097E-QINU`"'
'''Contraindicated in pregnancy''' (Category X); abortifacient and teratogenic. Discontinuation 3-6 months before conception is standard.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-000000BE-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-000004CF-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-0000056E-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-00000844-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, hypocalvaria, hypotension. Stop on detection'"`UNIQ--ref-00000AF0-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, skull hypoplasia, hypotension. Stop on detection'"`UNIQ--ref-0000005B-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, skull hypoplasia, hypotension. Stop on detection'"`UNIQ--ref-00000A24-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, skull hypoplasia, hypotension. Stop on detection'"`UNIQ--ref-00000B86-QINU`"'
'''Contraindicated in pregnancy''' (all trimesters); fetal renal injury, oligohydramnios, skull hypoplasia, hypotension'"`UNIQ--ref-00000C34-QINU`"'
'''Documented fetal growth restriction with chronic exposure'''; avoid in pregnancy if alternative β-blockers are appropriate. The β-blocker most consistently associated with intrauterine growth concerns'"`UNIQ--ref-00000022-QINU`"'
'''Pregnant individuals should not handle crushed/broken tablets''' (skin absorption risk); can cause hypospadias in male fetus. Not used in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
'''Pregnant individuals should not handle dutasteride capsules''' (skin absorption risk through intact capsule); can cause hypospadias in male fetus.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
'''Substantial teratogenic risk''' including cleft lip/palate, hypospadias, and growth restriction (pregnancy registry data clear); effective contraception and pre-pregnancy counseling are required in reproductive-age patients'"`UNIQ--ref-0000002A-QINU`"'
'''Substantial teratogenic risk''' including neural tube defects, craniofacial malformations, cardiac defects, and growth restriction; folic acid supplementation and effective contraception are required in reproductive-age patients'"`UNIQ--ref-0000001F-QINU`"'
Aminoglycoside-class ototoxicity in fetal cochlea is documented; use only when alternatives have failed.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid after 20 weeks (NSAID-class FDA 2020 advisory on fetal renal injury and oligohydramnios with second/third-trimester use).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid after 20 weeks (NSAID-class FDA 2020 advisory).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-00000022-QINU`"'
Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-00000028-QINU`"'
Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning; contraindicated from 30 weeks (risk of premature ductus arteriosus closure, which is paradoxically the basis of the neonatal PDA-closure indication)'"`UNIQ--ref-00000028-QINU`"'
Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning; contraindicated from 30 weeks. Specifically contraindicated in labor and delivery due to inhibition of uterine contractions'"`UNIQ--ref-00000022-QINU`"'
Avoid in pregnancy; antiandrogen effects can feminize a male fetus.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid in pregnancy; switch to LMWH. Crosses placenta; warfarin-class concerns about fetal hemorrhage and teratogenicity make heparins the preferred class.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid where possible; can reduce uteroplacental perfusion and produce neonatal electrolyte disturbance. Reserved for compelling indications.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid. Benzodiazepines are associated with neonatal sedation, floppy-infant syndrome, and withdrawal; teratogenic signal weak but non-zero. Designer benzo with no safety data, assume worst-case.
Avoid. Discontinue at least 1 month before planned pregnancy. Animal data show embryofetal harm.'"`UNIQ--ref-0000005B-QINU`"'
Avoid. Discontinue before planned pregnancy.'"`UNIQ--ref-000000EF-QINU`"'
Avoid. Discontinue before planned pregnancy.'"`UNIQ--ref-0000018C-QINU`"'
Avoid. Discontinue ≥1 month pre-conception. May reduce oral contraceptive efficacy during titration.'"`UNIQ--ref-00000304-QINU`"'
Avoid; NSAID-class restriction after 20 weeks (FDA 2020) and limited triptan pregnancy data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid; aspirin teratogenicity concerns plus opioid neonatal withdrawal.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid; may cause fetal harm
Avoid; neonatal opioid withdrawal documented.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated.
Avoid; switch to insulin. Hypoglycemia in newborn reported.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoid; switch to insulin. Neonatal hypoglycemia reported.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoided where possible; same class concerns as HCTZ.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Avoided; barbiturate + aspirin teratogenicity and bleeding concerns.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Category C (buprenorphine-only formulations preferred in pregnancy)
Category C (not relevant; not used in women)
Category C (per Desoxyn label)
Category C; limited data
Category C'"`UNIQ--ref-00000045-QINU`"'
Category C'"`UNIQ--ref-0000008F-QINU`"'
Category D'"`UNIQ--ref-0000006C-QINU`"'
Category X, contraindicated; teratogenic (virilization of female fetus)
Contraindicated in known pregnancy (Aygestin); the 0.35 mg POP is not teratogenic and does not need to be discontinued before conception planning.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Contraindicated in known pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Contraindicated in pregnancy (FDA label).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Contraindicated in pregnancy (only used in postmenopausal women); D class historically.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Contraindicated in pregnancy (use is not appropriate during gestation; class label X). Lactation considerations vary by indication.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Contraindicated in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Discontinued/withdrawn
Extensive use experience in obstetric anesthesia; broadly considered safe'"`UNIQ--ref-00000022-QINU`"'
First-line in pregnancy; dose typically increased 25-30% due to estrogen-driven rise in TBG and fetal demand. Lactation safe at physiologic doses.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally avoided in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally avoided; barbiturate exposure in late pregnancy can produce neonatal withdrawal and respiratory depression.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally avoided; fetal goiter/hypothyroidism risk (iodine load). Used only for life-threatening arrhythmia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally avoided; not first-line.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered acceptable for short-term use.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered acceptable when needed.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered acceptable.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe (minimal systemic exposure).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe after the first trimester; first-trimester use weighed against indication.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe at standard doses; benefits typically outweigh in active IBD.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe in pregnancy (no systemic absorption).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; commonly used in pregnancy when macrolide indicated.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; commonly used in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; loratadine and cetirizine have more pregnancy data and are typically preferred.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; pregnancy registries do not show increased major malformation risk.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used in PCOS and gestational diabetes; placental transfer occurs.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used in obstetric reflux.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used. Cetirizine and loratadine remain the more-studied alternatives.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used. Cleared in lactation at low levels.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used. Levocetirizine (the R-enantiomer) is an alternative with similar safety.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used. Loratadine and cetirizine are the most-recommended 2nd-gen H1s in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally considered safe; widely used.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally safe at replacement doses; treat the underlying cause of hypokalemia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Generally used when influenza treatment is indicated; pregnancy is a recognized risk factor for severe influenza.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
IV sulfate is the cornerstone of eclampsia/preeclampsia management; oral replacement also safe.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Inhaled and intranasal generally considered safe; widely used in asthma in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Insulin is the preferred glucose-lowering therapy in pregnancy; aspart is widely used.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Insulin is the preferred glucose-lowering therapy in pregnancy; degludec has reassuring observational data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Insulin is the preferred glucose-lowering therapy in pregnancy; glargine has reassuring observational data, though NPH and detemir remain the traditional choices.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Insulin is the preferred glucose-lowering therapy in pregnancy; lispro is widely used.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Intranasal long considered acceptable; widely used in obstetric rhinitis.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Investigational
Limit to <200 mg/d (~2 cups brewed)
Limited data; LABA/LAMA strategies in pregnancy generally favor agents with the most reassuring data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; National Pregnancy Registry available
Limited data; National Pregnancy Registry for Atypical Antipsychotics
Limited data; alternative antihypertensives generally preferred. Crosses placenta.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; avoid in pregnancy. Lactation: present in milk; consider risks
Limited data; case series and registries suggest no major teratogenicity but other antihypertensives (labetalol, nifedipine) are typically preferred.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; fluoxetine has reassuring data but olanzapine carries metabolic-syndrome and gestational diabetes signals.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; generally avoided in pregnancy for the cosmetic indication of onychomycosis.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; generally avoided particularly in combination with statin.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; generally avoided unless triglyceride pancreatitis risk is high.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; generally considered acceptable when needed.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; labetalol/nifedipine generally preferred. Crosses placenta.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; minimal systemic absorption likely renders fetal risk low.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; not first-line in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; pitolisant may reduce hormonal contraceptive efficacy
Limited data; pregnancy exposure registry available
Limited data; quinidine has been used in pregnancy as antiarrhythmic.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; rarely indicated in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; risk-benefit case by case; pregnancy is not a strict contraindication in WHO mass drug administration programs.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; second-line to intranasal corticosteroids or PO loratadine/cetirizine.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; weigh against alternatives (aspirin) where feasible.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; weigh against alternatives, though systemic exposure is low.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited data; weigh benefits/risks
Limited human data. Animal studies show fetal effects at maternally toxic doses; use only if benefits justify the potential risk.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; animal reproductive studies not conducted<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; case reports of neonatal sedation with late-pregnancy exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; endogenous hormone, but supplemental pharmacological doses are not well characterized in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; observational signals inconclusive.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; older agent with substantial use experience and no clear teratogenic signal.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; older agent with substantial use experience.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; older agent with substantial use experience; some signal for first-trimester exposure but not conclusive.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; pregnancy registry data have been broadly reassuring across the triptan class.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; pregnancy registry data have been broadly reassuring relative to baseline malformation rates.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; rarely indicated in pregnancy given the patient population.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; rarely indicated in pregnancy given the typical patient population.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; signal for neonatal extrapyramidal symptoms and withdrawal with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; some animal cardiac signal not clearly replicated in human cohort studies; observational signals inconclusive.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; some observational signals reassuring relative to other antidepressants.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; some signal for cardiac malformations and developmental delay but confounded by maternal disease and polytherapy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; some signal for cleft palate with first-trimester exposure (debated); neonatal sedation and withdrawal with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; the amphetamine class is associated with intrauterine growth restriction and neonatal withdrawal symptoms.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data; β-blocker class effects include fetal growth restriction and neonatal bradycardia/hypoglycemia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited human data<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited safety data; weigh benefit individually.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Limited use in pregnancy; chronic third-trimester opioid exposure produces neonatal opioid withdrawal syndrome and respiratory depression at delivery.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Long the preferred ICS in pregnancy (Pulmicort) due to the most pregnancy data among the class.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Long the preferred analgesic-antipyretic in pregnancy; recent observational studies have raised speculative neurodevelopmental signals that remain under investigation.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Long-considered safe in pregnancy for lupus and other rheumatologic indications; benefits typically outweigh.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Long-term skeletal retention is a concern given the unknown effect on developing fetal bone; generally avoided.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Low-dose (81 mg) safe and indicated for preeclampsia prophylaxis after 12 weeks in high-risk patients per USPSTF; high-dose aspirin avoid third trimester due to premature ductus arteriosus closure and bleeding risk
Medicine is structurally identical to endogenous allopregnanolone; pregnancy considerations relate to breastfeeding during/after infusion. Limited data; brief interruption of breastfeeding considered
Not absorbed; generally considered acceptable when bowel prep is required<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Not applicable (male indication); historical Category B if used in unrelated female cases.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Not established
Not indicated; pregnancy effects unknown
Not relevant (geriatric problem)
Not studied in human pregnancy; no approved clinical use in any population
Observational signal for neonatal adaptation syndrome with late-pregnancy exposure (SNRI class effect).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Observational signal for neonatal adaptation syndrome with late-pregnancy exposure; weigh against the risks of untreated maternal depression.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Observational signal for neonatal adaptation syndrome with third-trimester exposure (SSRI class effect).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Observational signal for persistent pulmonary hypertension of the newborn (small absolute risk) and neonatal adaptation syndrome with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Older agent with substantial use experience but limited controlled data; case reports of neonatal sedation and transient hypertension with maternal use near term.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Older agent with substantial use experience, including in hyperemesis gravidarum; broadly reassuring observational data'"`UNIQ--ref-00000024-QINU`"'
Older agent with substantial use experience; broadly considered safe in pregnancy'"`UNIQ--ref-00000028-QINU`"'
Older agent with substantial use experience; observational signals not clearly causal.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Older agent with substantial use experience; observational signals reassuring for first-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
One of the better-studied basal insulin analogs in pregnancy; reassuring data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
One of the historically preferred IV agents for severe hypertension in pregnancy alongside labetalol and nifedipine.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Oral nifedipine is one of the preferred agents for severe hypertension in pregnancy and for tocolysis in preterm labor.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Penicillin G is the only fully effective syphilis treatment in pregnancy; penicillin-allergic pregnant patients require desensitization.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Pharmacologic doses generally avoided in pregnancy; vitamin doses fine.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Preferred SABA in pregnancy; benefits of asthma control outweigh limited risks.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Pregnancy categories were retired by FDA in 2015. Limited reproductive data with small observational signal for cardiac malformations; risk-benefit decision, with many patients deferring ADHD treatment during pregnancy. See pregnancy_details for the full discussion.
Pregnancy categories were retired by FDA in 2015. Quetiapine has reassuring active-comparator cohort data without consistent teratogenic signal; among the preferred neuroleptics when treatment is clinically necessary in pregnancy. See pregnancy_details for the full citation set.
Previously Category X; FDA removed the blanket statin contraindication in pregnancy in 2021. Use individualized.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Previously Category X; FDA removed the blanket statin contraindication in pregnancy in 2021. Use individualized; lactation generally avoided.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Routine antacid and acidosis correction acceptable
Routinely supplemented in pregnancy and preconception to prevent neural tube defects.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Routinely supplemented in pregnancy; needs higher in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Routinely supplemented in vegan pregnancies and pernicious anemia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Routinely used; iron requirements rise substantially in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Safe at replacement and supplement doses.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Safe at replacement doses; deficiency is itself a risk in pregnancy and lactation.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Safe at replacement doses; high-dose use generally avoided.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Safe at routine doses; routinely supplemented in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Safe at routine fluoride levels.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Signal for gestational diabetes and metabolic syndrome with maternal exposure; the metabolic load can be substantial during pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Signal for neonatal extrapyramidal symptoms and withdrawal with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Some controversial signal for first-trimester gastroschisis association in observational studies; limited use is generally considered acceptable after the first trimester.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Some signal for cleft lip/palate with first-trimester exposure (debated); neonatal sedation and withdrawal with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Some signal for cleft palate with first-trimester exposure (debated); neonatal sedation and withdrawal with third-trimester exposure.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Some signal for major congenital malformations; limited human data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Standard fluid and electrolyte management
Standard resuscitation fluid in pregnancy
Substantial teratogenic signal (barbiturate class effects including neonatal withdrawal and hemorrhagic disease of newborn).<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Synthetic levothyroxine is the standard-of-care in pregnancy; desiccated thyroid use in pregnancy is not well studied<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
T4 (levothyroxine) is the first-line in pregnancy; T3 is rarely needed.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
TCA class signal; limited human data specific to doxepin.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
TCA class signal; limited human data specific to nortriptyline.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Teratogenic signal less than carbamazepine but present; folate supplementation and effective contraception are appropriate in reproductive-age patients'"`UNIQ--ref-0000001C-QINU`"'
Topical and vaginal generally considered safe; widely used.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Topical corticosteroids in pregnancy: use lowest potency and smallest area; super-potent agents like clobetasol are reserved for compelling indications.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Topical generally safe; oral avoided.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Topical/intranasal generally low-risk; intra-articular and high-dose injection: weigh risk individually.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Topical: avoid; systemic: contraindicated in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Use in fetal SVT (transplacental antiarrhythmic therapy) is established; otherwise weigh against alternatives.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Use when benefits outweigh; small association with oral clefts debated.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Use when benefits outweigh; small association with oral clefts in first trimester debated.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Use when benefits outweigh; widely used at physiologic doses for adrenal insufficiency.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Used in FMF in pregnancy; otherwise weigh against alternatives.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Used in antenatal lung maturation (24-34 weeks gestation; 6 mg IM q12h × 4 doses); broader use weighs benefits against fetal HPA suppression.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Used in life-threatening obstetric anaphylaxis without hesitation; benefits clearly outweigh.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Used in obstetric emergencies (uterine relaxation, severe hypertension) when needed; otherwise limited routine use.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Used in transplant pregnancy when continued immunosuppression is required; reassuring data overall but careful monitoring needed.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Used when benefits outweigh risk; oral cleft signal in first-trimester exposure is debated and small in absolute terms.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Used when needed for hypoparathyroidism or renal osteodystrophy in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Widely used for hyperemesis gravidarum; reassuring data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Widely used in obstetric reflux; reassuring data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Widely used in pregnancy for HSV/VZV indications; reassuring registry data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Widely used in pregnancy when antiviral indicated; reassuring registry data.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
Widely used in pregnancy; meta-analyses do not show increased malformation risk.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup>
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