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Medicines > classes: [[:Category:Neuraminidase_inhibitors|Neuraminidase inhibitor]] & duration : 12 hours or 24 hours (once-daily dosing)

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generic:
Oseltamivir (1)
brand:
Tamiflu (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000E91-QINU`"', '"`UNIQ--vote-00000E92-QINU`"', '"`UNIQ--vote-00000E93-QINU`"' (1)
starting dose:
Treatment: 75 mg PO BID × 5 days (adult); pediatric weight-based; prophylaxis: 75 mg PO once daily × 7-10 days (1)
preparations:
30, 45, 75 mg capsules; 6 mg/mL oral suspension (1)
fda max:
150 mg/d (treatment) (1)
routes:
Oral (1)
onset:
Symptom shortening detectable within 24-48 hours of starting (small absolute benefit; ~1 day reduction in symptom duration) (1)
duration: (Click arrow to add another value)
halflife:
~6-10 hours (oseltamivir carboxylate, the active metabolite)'"`UNIQ--ref-00000E94-QINU`"' (1)
bioavailability:
~75% (oral, as the active carboxylate after hepatic esterase activation)'"`UNIQ--ref-00000E95-QINU`"' (1)
pregnancy:
Generally used when influenza treatment is indicated; pregnancy is a recognized risk factor for severe influenza.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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