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Drilldown: Medicines

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Medicines > classes: [[:Category:SSRIs|Selective serotonin reuptake inhibitor (SSRI)]] & halflife: ~15 hours (IR)'"`UNIQ--ref-00000023-QINU`"'

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generic:
Fluvoxamine (maleate) (1)
brand:
Luvox (US brand discontinued; generic widely available), Luvox CR, Faverin (other markets) (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"' (1)
starting dose:
50 mg PO at bedtime; titrate by 50 mg every 4-7 days to clinical effect. Total daily doses >100 mg divided BID. Luvox CR: 100 mg PO once daily, may titrate to 300 mg/day (1)
preparations:
IR tablets 25, 50, 100 mg; Luvox CR capsules 100, 150 mg (1)
fda max:
300 mg/day (IR or CR) (1)
routes:
Oral (1)
onset:
OCD effect over 1-2 weeks initial, with full effect typically 6-12 weeks; among the slowest SSRIs for OCD response (1)
duration:
BID at higher doses (IR); once-daily (CR) (1)
halflife: (Click arrow to add another value)
bioavailability:
~53% (oral)'"`UNIQ--ref-00000024-QINU`"' (1)
pregnancy:
Observational signal for neonatal adaptation syndrome with third-trimester exposure (SSRI class effect).<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US. Carries the antidepressant '''Boxed Warning''' for suicidality in children, adolescents, and young adults'"`UNIQ--ref-00000025-QINU`"' (1)
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