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Medicines > classes: [[:Category:SV2A ligands|Synaptic vesicle protein 2A (SV2A) ligand]] & fda max: 3000 mg/day

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generic:
Levetiracetam (1)
brand:
Keppra (IR), Keppra XR, Spritam (3D-printed orally disintegrating), Roweepra (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"' (1)
starting dose:
Adult: 500 mg PO BID, titrate by 1000 mg/day every 2 weeks. Pediatric: 10-20 mg/kg/day divided BID, weight-titrated (1)
preparations:
IR tablets 250, 500, 750, 1000 mg; XR tablets 500, 750 mg; oral solution 100 mg/mL; injection 100 mg/mL; Spritam ODT 250, 500, 750, 1000 mg (1)
fda max: (Click arrow to add another value)
routes:
intravenous (1) · Oral (1)
onset:
Anticonvulsant effect within days at therapeutic plasma level; rapid titration possible (1)
duration:
BID dosing (IR); once-daily (XR) (1)
halflife:
6-8 hours'"`UNIQ--ref-0000001F-QINU`"' (1)
bioavailability:
~100% (oral)'"`UNIQ--ref-00000020-QINU`"' (1)
pregnancy:
'''Considered one of the safest anticonvulsants in pregnancy''', with reassuring monotherapy registry data comparable to lamotrigine and in sharp contrast to valproate, topiramate, and carbamazepine'"`UNIQ--ref-00000021-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US. Not a controlled substance'"`UNIQ--ref-00000022-QINU`"' (1)

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