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Medicines > classes: [[:Category:Sodium channel blockers|Sodium channel blocker]] & onset: Anticonvulsant effect within days at therapeutic plasma level & duration: BID dosing (IR); once-daily (XR)

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generic:
Oxcarbazepine (1)
brand:
Trileptal (IR), Oxtellar XR (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000017-QINU`"', '"`UNIQ--vote-00000018-QINU`"', '"`UNIQ--vote-00000019-QINU`"' (1)
starting dose:
Adult monotherapy: 300 mg PO BID, titrate by 300 mg every 3 days. Pediatric: weight-based titration starting 8-10 mg/kg/day divided BID (1)
preparations:
IR tablets 150, 300, 600 mg; oral suspension 60 mg/mL; XR tablets 150, 300, 600 mg (Oxtellar) (1)
fda max:
2400 mg/day (adult) (1)
routes:
Oral (1)
onset: (Click arrow to add another value)
duration: (Click arrow to add another value)
halflife:
Oxcarbazepine 2 hours; '''10-monohydroxy active metabolite (MHD) ~9 hours''' (the agent that produces essentially all of the clinical effect)'"`UNIQ--ref-0000001A-QINU`"' (1)
bioavailability:
~100% (oral)'"`UNIQ--ref-0000001B-QINU`"' (1)
pregnancy:
Teratogenic signal less than carbamazepine but present; folate supplementation and effective contraception are appropriate in reproductive-age patients'"`UNIQ--ref-0000001C-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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