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Medicines > classes: [[:Category:Sulfonylureas|Sulfonylurea (third-generation)]] & onset : 1-2 hours or AF conversion within hours of single PO dose

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generic:
Glimepiride (1)
brand:
Amaryl (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000491-QINU`"' (1)
starting dose:
1-2 mg PO once daily with breakfast; titrate by glycemic response (1)
preparations:
1 mg, 2 mg, 4 mg tablets (1)
fda max:
8 mg/d (1)
routes:
Oral (1)
onset: (Click arrow to add another value)
duration:
24 hours (1)
halflife:
~5-9 hours (parent and active metabolites combined)'"`UNIQ--ref-00000492-QINU`"' (1)
bioavailability:
~100% (oral; not significantly affected by food)'"`UNIQ--ref-00000493-QINU`"' (1)
pregnancy:
Avoid; switch to insulin. Neonatal hypoglycemia reported.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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