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Medicines > classes: [[:Category:Vitamin_D_analogs|Vitamin D analog (active form)]] & onset: Days for calcium effect; weeks for PTH suppression

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generic:
Calcitriol (1,25-dihydroxyvitamin D3) (1)
brand:
Rocaltrol (oral), Calcijex (IV); topical Vectical for psoriasis (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000115F-QINU`"', '"`UNIQ--vote-00001160-QINU`"', '"`UNIQ--vote-00001161-QINU`"', '"`UNIQ--vote-00001162-QINU`"', '"`UNIQ--vote-00001163-QINU`"' (1)
starting dose:
Oral 0.25 mcg daily, titrate by serum calcium and PTH; IV in CKD 0.5-3 mcg three times weekly (1)
preparations:
0.25, 0.5 mcg oral capsules; 1 mcg/mL oral solution; 1 mcg/mL IV; 3 mcg/g topical ointment (1)
fda max:
Titrated; risk of hypercalcemia is the limiting factor (1)
routes:
IV (1) · Oral (1) · topical (1)
onset: (Click arrow to add another value)
duration:
Hours per dose (much shorter biologic effect than ergocalciferol/cholecalciferol because it is the already-active form, not the storage form) (1)
halflife:
~5-8 hours'"`UNIQ--ref-00001164-QINU`"' (1)
bioavailability:
High (oral)'"`UNIQ--ref-00001165-QINU`"' (1)
pregnancy:
Used when needed for hypoparathyroidism or renal osteodystrophy in pregnancy.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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