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Medicines > classes: [[:Category:Vitamins|Vitamin]] & onset : Hematologic response within days or Sleep effect from first dose; antidepressant effect over 1-4 weeks

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generic:
Folic acid (folate, pteroylglutamic acid) (1)
brand:
Folvite; mostly generic (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-000005B3-QINU`"', '"`UNIQ--vote-000005B4-QINU`"', '"`UNIQ--vote-000005B5-QINU`"', '"`UNIQ--vote-000005B6-QINU`"' (1)
starting dose:
0.4 mg PO daily (general prevention); 0.8-1 mg/d in pregnancy; 4 mg/d for women with prior NTD-affected pregnancy; 1 mg/d during methotrexate therapy (1)
preparations:
0.4, 0.8, 1 mg OTC; 1 mg Rx; 5 mg/mL injection (1)
fda max:
1 mg/d typical Rx; higher in specific indications (1)
routes:
IM (1) · IV (1) · Oral (1) · SC (1)
onset: (Click arrow to add another value)
duration:
N/A (replacement) (1)
halflife:
~0.5 hours plasma; tissue retention longer (1)
bioavailability:
High (oral) (1)
pregnancy:
Routinely supplemented in pregnancy and preconception to prevent neural tube defects.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
OTC (low-dose) and [[USLegal:Prescription only|Rx-only]] (1 mg, injectable) in US (1)

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