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Drilldown: Medicines

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Medicines > classes: 5HT2A/D2 antagonist with proposed differential pre/post-synaptic D2 activity & halflife: ~18 hours (terminal)

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generic:
None (1)
brand:
Caplyta (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
Schizophrenia (FDA-approved Dec 2019). Bipolar depression as monotherapy or adjunct to lithium/valproate (FDA-approved Dec 2021). (1)
starting dose:
42 mg PO once daily with food (no titration) (1)
preparations:
42 mg capsules (1)
fda max:
42 mg/d (1)
routes:
Oral (1)
onset:
Antipsychotic effect over weeks (1)
duration:
Daily dosing (1)
halflife: (Click arrow to add another value)
bioavailability:
Limited but adequate; take with food (1)
pregnancy:
Limited data; National Pregnancy Registry for Atypical Antipsychotics (1)
legal:
Rx (1)

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