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Drilldown: Medicines

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Medicines > classes: Excitantia & onset : 15–30 min or HbA1c effect at 12-16 weeks (slower than other classes)

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generic:
Khat (1) · Tea (1)
brand:
''Camellia sinensis'' (formerly ''Thea sinensis'') (1) · ''Catha edulis''. Chat, qat, the Flower of Paradise (1)
classes: (Click arrow to add another value)
mechanism:
Caffeine + theophylline + L-theanine. L-theanine (an amino acid unique to tea) modulates glutamate and produces an 'alpha-wave' calming overlay on caffeine's stimulation, hence tea's reputation as a 'cleaner' stimulant than coffee. (1) · Primary alkaloid is (S)-(-)-cathinone, a phenylpropanolamine close kin to amphetamine. Releases dopamine and norepinephrine. Also contains cathine (=norpseudoephedrine) and norephedrine. (1)
uses:
'"`UNIQ--vote-00000008-QINU`"', '"`UNIQ--vote-00000009-QINU`"' (1) · '"`UNIQ--vote-00000747-QINU`"', '"`UNIQ--vote-00000748-QINU`"' (1)
starting dose:
A ''marduuf'' bundle (~50 g fresh leaves) chewed over a couple of hours (1) · One cup (~40–60 mg caffeine; about half of brewed coffee) (1)
preparations:
Dried leaves, infused. Six major processings: white, green, yellow, oolong, black, pu-erh (1) · Fresh leaves and tender twigs chewed; degrades on drying (1)
fda max:
None (2)
routes:
Oral (1) · Oral (buccal absorption) (1)
onset: (Click arrow to add another value)
duration:
2–4 h (1) · 3–4 h (1)
halflife:
None (1) · ~5 h (caffeine) (1)
bioavailability:
None (2)
pregnancy:
None (2)
legal:
None (1) · Schedule I in US since 1993 (despite traditional use elsewhere); legal in Ethiopia, Kenya, Yemen, Somalia, Djibouti (1)
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