Jump to content

Drilldown: Medicines

Choose a table:


Medicines > generic: None & classes: GABA-A positive allosteric modulator & duration: Single infusion course

Use the filters below to narrow your results.

generic: (Click arrow to add another value)
brand:
Zulresso (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
Postpartum depression (PPD) in adults (1)
starting dose:
Single 60-hour continuous IV infusion: 30 mcg/kg/h × 4h → 60 mcg/kg/h × 20h → 90 mcg/kg/h × 28h → 60 mcg/kg/h × 4h → 30 mcg/kg/h × 4h (1)
preparations:
100 mg/20 mL vial, single-use (1)
fda max:
Single 60-hour course (1)
routes:
Intravenous (continuous infusion in a REMS-certified facility) (1)
onset:
Antidepressant effect within hours of infusion start; sustained at 30 days (1)
duration: (Click arrow to add another value)
halflife:
~9 hours (terminal) (1)
bioavailability:
100% (IV) (1)
pregnancy:
Medicine is structurally identical to endogenous allopregnanolone; pregnancy considerations relate to breastfeeding during/after infusion. Limited data; brief interruption of breastfeeding considered (1)
legal:
Rx; REMS program required (excessive sedation/loss of consciousness during infusion) (1)

Showing below up to 1 result in range #1 to #1.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"