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Drilldown: Medicines

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Medicines > classes: Multimodal serotonergic; HSDD treatment & onset : BP effect within 1-2 weeks or Effects accumulate over weeks; assess at 8 weeks

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generic:
Flibanserin (1)
brand:
Addyi (1)
classes: (Click arrow to add another value)
mechanism:
5-HT1A agonist, 5-HT2A antagonist, with weaker activity at D4 and other receptors. Net effect involves enhanced prefrontal dopaminergic/noradrenergic tone with decreased serotonergic inhibition of sexual desire. (1)
uses:
'"`UNIQ--vote-000002C1-QINU`"' (1)
starting dose:
100 mg at bedtime daily (1)
preparations:
100 mg tabs (1)
fda max:
100 mg/d (1)
routes:
Oral (1)
onset: (Click arrow to add another value)
duration:
Continuous daily dosing (1)
halflife:
~11 h (1)
bioavailability:
~33% (1)
pregnancy:
Not indicated; pregnancy effects unknown (1)
legal:
Rx-only in US (REMS program) (1)

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