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Drilldown: Medicines

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Medicines > generic: Propranolol & classes: Non-selective & fda max: 640 mg/d (HTN); 240 mg/d (migraine)

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generic: (Click arrow to add another value)
brand:
Inderal (1)
classes: (Click arrow to add another value)
mechanism:
Non-selective competitive antagonist at β1 and β2 adrenergic receptors. Lipophilic; significant blood–brain barrier penetration, accounting for its CNS effects. (1)
uses:
'"`UNIQ--vote-000005E7-QINU`"', '"`UNIQ--vote-000005E8-QINU`"', '"`UNIQ--vote-000005E9-QINU`"', '"`UNIQ--vote-000005EA-QINU`"', '"`UNIQ--vote-000005EB-QINU`"' (1)
starting dose:
10–40 mg (situational anxiety); 40 mg BID (HTN) (1)
preparations:
10, 20, 40, 60, 80 mg tabs; 60/80/120/160 mg ER caps; 1 mg/mL IV (1)
fda max: (Click arrow to add another value)
routes:
IV (1) · Oral (1)
onset:
1–2 h (PO), immediate (IV) (1)
duration:
6–12 h (IR); 24 h (ER) (1)
halflife:
3–6 h (1)
bioavailability:
~25% (extensive hepatic first-pass) (1)
pregnancy:
Category C (1)
legal:
Rx-only in US (1)

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