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Medicines > classes: PDE5 Inhibitor & onset : AF conversion within hours of single PO dose or ~30 min

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generic:
Vardenafil (1)
brand:
Levitra, Staxyn (1)
classes: (Click arrow to add another value)
mechanism:
Selective inhibitor of PDE5. Slightly higher PDE5/PDE6 selectivity vs sildenafil (less visual side effect) but more PDE1 cross-activity (occasional QT effects at high doses). (1)
uses:
'"`UNIQ--vote-00000669-QINU`"' (1)
starting dose:
10 mg ~1 h before sexual activity (1)
preparations:
2.5, 5, 10, 20 mg tabs (Levitra); 10 mg ODT (Staxyn) (1)
fda max:
20 mg/d (1)
routes:
Oral (1)
onset: (Click arrow to add another value)
duration:
4–5 h (1)
halflife:
4–5 h (1)
bioavailability:
~15% (extensive hepatic first-pass) (1)
pregnancy:
Category B (1)
legal:
Rx-only in US (1)

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