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Medicines > classes: Plant Medicine & halflife : 1-3 minutes (very short)'"`UNIQ--ref-00000C0F-QINU`"' or ~5 h (caffeine)

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generic:
Coffee (1) · Tea (1)
brand:
''Camellia sinensis'' (formerly ''Thea sinensis'') (1) · ''Coffea arabica'', ''Coffea canephora'' (robusta) (1)
classes: (Click arrow to add another value)
mechanism:
Caffeine + theophylline + L-theanine. L-theanine (an amino acid unique to tea) modulates glutamate and produces an 'alpha-wave' calming overlay on caffeine's stimulation, hence tea's reputation as a 'cleaner' stimulant than coffee. (1) · Caffeine is a non-selective adenosine A1/A2A receptor antagonist; also weak PDE inhibition. Beans contain theobromine (3,7-DMX) and theophylline (1,3-DMX) in smaller amounts. (1)
uses:
'"`UNIQ--vote-000000CF-QINU`"', '"`UNIQ--vote-000000D0-QINU`"', '"`UNIQ--vote-000000D1-QINU`"' (1) · '"`UNIQ--vote-00000747-QINU`"', '"`UNIQ--vote-00000748-QINU`"' (1)
starting dose:
One cup (~40–60 mg caffeine; about half of brewed coffee) (1) · One cup (~80–145 mg caffeine for brewed; 60–100 mg for instant) (1)
preparations:
Dried leaves, infused. Six major processings: white, green, yellow, oolong, black, pu-erh (1) · Roasted beans, ground; brewed (drip, French press, espresso, cold brew, percolated) (1)
fda max:
None (2)
routes:
Oral (2)
onset:
15–30 min (1) · ~15–30 min (1)
duration:
3–4 h (1) · 3–5 h (subjective) (1)
halflife: (Click arrow to add another value)
bioavailability:
None (1) · ~99% (caffeine) (1)
pregnancy:
None (1) · Limit to <200 mg/d (~2 cups brewed) (1)
legal:
None (1) · Unrestricted (food) (1)
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