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Drilldown: Medicines

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Medicines > generic: None & classes: Serotonin partial agonist reuptake inhibitor (SPARI) & halflife: ~25 hours

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generic: (Click arrow to add another value)
brand:
Viibryd (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
Major depressive disorder in adults (FDA-approved 2011) (1)
starting dose:
10 mg PO once daily × 7 days, then 20 mg × 7 days, then 40 mg as target dose (take with food) (1)
preparations:
10 mg, 20 mg, 40 mg tablets (1)
fda max:
40 mg/d (1)
routes:
Oral (1)
onset:
4-6 weeks for full antidepressant effect (claimed earlier onset for some patients due to 5HT1A partial agonism) (1)
duration:
Daily dosing (1)
halflife: (Click arrow to add another value)
bioavailability:
~72% (with food); much lower fasting (~36%) (1)
pregnancy:
Limited data; weigh benefits/risks (1)
legal:
Rx (1)

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