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Medicines > classes: non-selective)]] & fda max: 3200 mg/day (Rx); 1200 mg/day (OTC, without provider direction) & routes: NeoProfen)

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generic:
Ibuprofen (1)
brand:
Advil, Motrin, IBU, Caldolor (IV), NeoProfen (neonatal IV) (1)
classes: (Click arrow to add another value)
mechanism:
None (1)
uses:
'"`UNIQ--vote-0000001F-QINU`"', '"`UNIQ--vote-00000020-QINU`"', '"`UNIQ--vote-00000021-QINU`"', '"`UNIQ--vote-00000022-QINU`"', '"`UNIQ--vote-00000023-QINU`"', '"`UNIQ--vote-00000024-QINU`"', '"`UNIQ--vote-00000025-QINU`"' (1)
starting dose:
200-400 mg PO every 4-6 hours as needed. OTC max 1200 mg/day without provider direction; prescription max 3200 mg/day divided (1)
preparations:
Tablets 200, 400, 600, 800 mg; capsules 200 mg; oral suspension 100 mg/5 mL; chewable tablets 100 mg; injection 100 mg/mL (Caldolor) (1)
fda max: (Click arrow to add another value)
routes: (Click arrow to add another value)
onset:
30-60 minutes (oral) (1)
duration:
4-6 hours (1)
halflife:
2-4 hours'"`UNIQ--ref-00000026-QINU`"' (1)
bioavailability:
~80-100% (oral)'"`UNIQ--ref-00000027-QINU`"' (1)
pregnancy:
Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-00000028-QINU`"' (1)
legal:
[[USLegal:Over-the-counter|OTC]] in the US at ≤200 mg per tablet / ≤1200 mg/day; [[USLegal:Prescription only|Rx-only]] at higher strengths and indications (1)

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