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Medicines (732)

Medicines > classes: with mineralocorticoid activity)]]

& onset

: 5-10 minutes (IV); 30 minutes (oral IR); slower for ER and rectal

or Hours

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Hydrocortisone (cortisol) (1)

Cortef (oral), Solu-Cortef (IV), many topical brands (Cortizone, OTC); Plenadren, Alkindi (modified-release for adrenal insufficiency) (1)

None (1)

'"`UNIQ--vote-00000ACD-QINU`"', '"`UNIQ--vote-00000ACE-QINU`"', '"`UNIQ--vote-00000ACF-QINU`"', '"`UNIQ--vote-00000AD0-QINU`"' (1)

Physiologic replacement 15-25 mg/d divided (e.g., 10 mg AM, 5 mg noon, 5 mg afternoon); stress dose 50-100 mg IV q6-8h; adrenal crisis 100 mg IV then 50-100 mg q6h; topical 0.5-2.5% applied 2-4×/d (1)

5, 10, 20 mg oral tablets; 100, 250, 500, 1000 mg IV (Solu-Cortef); 0.5%, 1%, 2.5% topical creams/ointments; rectal foam and enemas (1)

Indication-specific (1)

IM (1) · IV (1) · Oral (1) · rectal (1) · topical (1)

Biologic ~8-12 hours (short-acting) (1)

Plasma ~1-2 hours; biologic ~8-12 hours'"`UNIQ--ref-00000AD1-QINU`"' (1)

~96% (oral)'"`UNIQ--ref-00000AD2-QINU`"' (1)

Use when benefits outweigh; widely used at physiologic doses for adrenal insufficiency.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

OTC (low-dose topicals) and [[USLegal:Prescription only|Rx-only]] (other forms) in US (1)

Showing below up to 1 result in range #1 to #1.

H

Hydrocortisone

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