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Drilldown: Medicines

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Medicines > fda max: 200 mg/d (100 mg/d if on CYP3A4 inhibitors) & duration : 4-6 hours (IR); 24 hours (ER) or 4–6 h

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generic:
Avanafil (1)
brand:
Stendra (1)
classes:
PDE5 Inhibitor (1)
mechanism:
Selective inhibitor of phosphodiesterase type 5 (PDE5); increases cGMP in cavernous smooth muscle, producing erection in response to sexual stimulation. (1)
uses:
'"`UNIQ--vote-00000040-QINU`"' (1)
starting dose:
100 mg ~15 min before sexual activity (1)
preparations:
50, 100, 200 mg tabs (1)
fda max: (Click arrow to add another value)
routes:
Oral (1)
onset:
~15 min (fastest of the PDE5 inhibitors) (1)
duration: (Click arrow to add another value)
halflife:
~5 h (1)
bioavailability:
Rapid absorption; absolute bioavailability not formally established (1)
pregnancy:
Category C (not relevant; not used in women) (1)
legal:
Rx-only in US (1)

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