Drilldown: Medicines

None (1)

Ajovy (1)

Anti-CGRP ligand monoclonal antibody (1)

Humanized IgG2 monoclonal antibody binding both isoforms of CGRP peptide (1)

Preventive treatment of migraine in adults (episodic and chronic) (1)

225 mg SC monthly, or 675 mg SC every 3 months (quarterly) (1)

225 mg/1.5 mL prefilled syringe or autoinjector (1)

675 mg/quarter (1)

Subcutaneous (1)

None · Hours · 30-60 minutes · 1-2 hours · ~30 min · LDL lowering at 2 weeks, max by 4 weeks · ~1 hour · 15-30 minutes · 15–30 min · 1–2 h · 30–60 min · Antidepressant effect emerges over 1-2 weeks · BP and symptomatic LUTS improvement within 1-2 weeks · BP effect within 1-2 weeks · Clinical improvement within 24-72 hours · Days · Motor improvement over days at therapeutic dose · Over weeks · Postprandial glucose effect within days; HbA1c by 12 weeks · Sleep effect from first dose; antidepressant effect over 1-4 weeks

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None · 24 hours · 4-6 hours · 12 hours · 6-8 hours · Daily dosing · 8-12 hours · 12-24 hours · Hours · Hours per application · 24 hours (HS dosing) · 24 hours (once-daily dosing) · 24 h · N/A · N/A (replacement) · Variable · ~7-8 hours · 3-5 hours · 4-6 hours (IR); 24 hours (ER) · 6-12 hours

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~31 days (1)

Not formally established (1)

Limited data; avoid (1)

Rx (1)