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Medicines (732)

Medicines > routes: IV

& duration

: N/A (replacement)

or Variable; depends on ongoing losses

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Cyanocobalamin (vitamin B12) (1) · Folic acid (folate, pteroylglutamic acid) (1) · Potassium chloride (1)

Folvite; mostly generic (1) · K-Dur, Klor-Con, Slow-K, Micro-K, K-Lyte/Cl (1) · Many OTC and Rx; Nascobal (intranasal); generic injection (1)

[[:Category:B-vitamins|B-vitamin]] (2) · [[:Category:Electrolyte_replacements|Electrolyte replacement]] (1) · [[:Category:Hematinics|Hematinic]] (2) · [[:Category:Potassium_supplements|Potassium supplement]] (1) · [[:Category:Vitamins|Vitamin]] (2)

None (3)

'"`UNIQ--vote-000002EE-QINU`"', '"`UNIQ--vote-000002EF-QINU`"' (1) · '"`UNIQ--vote-000005B3-QINU`"', '"`UNIQ--vote-000005B4-QINU`"', '"`UNIQ--vote-000005B5-QINU`"', '"`UNIQ--vote-000005B6-QINU`"' (1) · '"`UNIQ--vote-00000607-QINU`"', '"`UNIQ--vote-00000608-QINU`"', '"`UNIQ--vote-00000609-QINU`"', '"`UNIQ--vote-0000060A-QINU`"' (1)

0.4 mg PO daily (general prevention); 0.8-1 mg/d in pregnancy; 4 mg/d for women with prior NTD-affected pregnancy; 1 mg/d during methotrexate therapy (1) · 10-20 mEq PO daily for prevention; treat established hypokalemia per measured deficit, typically 40-100 mEq/d in divided doses; IV 10 mEq/h peripheral, 20 mEq/h central with telemetry (1) · Replacement: 1000 mcg IM daily for 1 week, then weekly for 4 weeks, then monthly; or 1000-2000 mcg PO daily (effective even in pernicious anemia via passive diffusion); intranasal 500 mcg weekly (1)

0.4, 0.8, 1 mg OTC; 1 mg Rx; 5 mg/mL injection (1) · 100, 250, 500, 1000, 5000 mcg tablets (OTC and Rx); 1000 mcg/mL injection; intranasal spray; sublingual (1) · 8, 10, 20, 25 mEq tablets/capsules (most ER); effervescent and oral solution; IV concentrate (must be diluted) (1)

1 mg/d typical Rx; higher in specific indications (1) · IV peripheral 10 mEq/h (40 mEq/L); IV central 20 mEq/h with cardiac monitoring; PO single doses generally ≤40 mEq (1) · No strict ceiling; water-soluble vitamin, low toxicity (1)

Hematologic response within days (1) · Hours (PO); IV faster but rate-limited (1) · Reticulocyte response at 3-5 days; neurologic recovery weeks to months (and may be incomplete if longstanding) (1)

Not meaningfully described for an electrolyte; distribution between intra- and extracellular compartments is the relevant kinetic (1) · ~0.5 hours plasma; tissue retention longer (1) · ~6 days (plasma); hepatic stores last 3-5 years (1)

60-80% (oral) (1) · High (oral) (1) · Oral ~1-3% via passive diffusion at high doses (independent of intrinsic factor); IM/SC ~100% (1)

Generally safe at replacement doses; treat the underlying cause of hypokalemia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) · Routinely supplemented in pregnancy and preconception to prevent neural tube defects.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) · Routinely supplemented in vegan pregnancies and pernicious anemia.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1)

OTC (low-dose) and [[USLegal:Prescription only|Rx-only]] (1 mg, injectable) in US (1) · OTC (low/mid-dose oral) and [[USLegal:Prescription only|Rx-only]] (injection, intranasal) in US (1) · [[USLegal:Prescription only|Rx-only]] (higher concentrations and IV) and OTC (low-dose supplements) in US (1)

Showing below up to 3 results in range #1 to #3.

C

Cyanocobalamin

F

Folic Acid

P

Potassium Chloride

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