Jump to content

Drilldown: Medicines

Choose a table:


Medicines > generic : 2-FMA or None & duration: 14-day course; effect persists after discontinuation in trials

Use the filters below to narrow your results.

generic: (Click arrow to add another value)
brand:
Zurzuvae (1)
classes:
GABA-A positive allosteric modulator (oral) (1) · Neuroactive steroid (1)
mechanism:
Synthetic neuroactive steroid (an analog of allopregnanolone), bioavailable orally unlike brexanolone. Positive allosteric modulator at GABA-A receptors including extrasynaptic δ-containing subtypes. (1)
uses:
Postpartum depression (PPD) in adults (FDA-approved 2023) (1)
starting dose:
50 mg PO once daily with fatty food in the evening × 14 days (1)
preparations:
20 mg, 25 mg, 30 mg capsules (1)
fda max:
50 mg/d × 14 d (1)
routes:
Oral (1)
onset:
Day 3 of dosing in trials; sustained through day 45 (1)
duration: (Click arrow to add another value)
halflife:
~16-23 hours (1)
bioavailability:
Adequate (food-dependent, must take with fatty meal) (1)
pregnancy:
Limited data; avoid in pregnancy. Lactation: present in milk; consider risks (1)
legal:
Rx, Schedule IV (US) (1)

Showing below up to 1 result in range #1 to #1.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"