Jump to content

Drilldown: Medicines

Pharmacopedia
BrowseCategoriesLog in

Choose a table:


Medicines > generic: Memantine ER / Donepezil & routes: Oral (capsule whole or opened/sprinkled on applesauce) & duration: 24 h

Use the filters below to narrow your results.

generic: (Click arrow to add another value)
brand:
Namzaric (1)
classes:
Combined cholinesterase inhibitor + NMDA antagonist (1)
mechanism:
Donepezil: reversible AChE inhibitor, increases synaptic acetylcholine. Memantine: uncompetitive low-affinity NMDA receptor antagonist, dampens pathological glutamate overactivation while preserving normal synaptic signaling. Targets two distinct mechanisms in Alzheimer's. (1)
uses:
'"`UNIQ--vote-00000468-QINU`"' (1)
starting dose:
For patients already stable on memantine 28 mg/d + donepezil 10 mg/d, switch to one capsule daily of equivalent strength (1)
preparations:
7/10, 14/10, 21/10, 28/10 mg ER capsules (memantine ER / donepezil) (1)
fda max:
28/10 mg/d (1)
routes: (Click arrow to add another value)
onset:
Component effects accumulate over weeks (1)
duration: (Click arrow to add another value)
halflife:
~60–80 h (memantine); ~70 h (donepezil) (1)
bioavailability:
~100% both components (1)
pregnancy:
Not relevant (geriatric problem) (1)
legal:
Rx-only in US (1)

Showing below up to 1 result in range #1 to #1.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"