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Medicines > generic : 1,4-Butanediol or Dutasteride & duration: 24 hours; tissue effects persist weeks

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generic: (Click arrow to add another value)
brand:
Avodart; combined with tamsulosin as Jalyn (1)
classes:
[[:Category:5-alpha-reductase_inhibitors|5α-reductase inhibitor (dual type I/II)]] (1) · [[:Category:Androgen_modulators|Androgen modulator]] (1) · [[:Category:BPH_treatments|Benign prostatic hyperplasia treatment]] (1)
mechanism:
None (1)
uses:
'"`UNIQ--vote-00000D57-QINU`"', '"`UNIQ--vote-00000D58-QINU`"' (1)
starting dose:
0.5 mg PO once daily (1)
preparations:
0.5 mg capsules (1)
fda max:
0.5 mg/d (1)
routes:
Oral (1)
onset:
Prostate volume reduction over 6-12 months (1)
duration: (Click arrow to add another value)
halflife:
~5 weeks (much longer than finasteride's ~6 hours)'"`UNIQ--ref-00000D59-QINU`"' (1)
bioavailability:
~60% (oral)'"`UNIQ--ref-00000D5A-QINU`"' (1)
pregnancy:
'''Pregnant individuals should not handle dutasteride capsules''' (skin absorption risk through intact capsule); can cause hypospadias in male fetus.<sup class="pcp-cn" title="This claim needs a citation.">&#91;[[Pharmacopedia:Citation needed|citation&nbsp;needed]]&#93;</sup> (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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